Dilute Betadine Lavage Before Closure for the Prevention of Acute Postoperative Deep Periprosthetic Joint Infection
Abstract This study evaluated the efficacy of a dilute Betadine (Purdue Pharma, Stamford, Conn) lavage in preventing early deep postoperative infection after total hip (THA) and knee (TKA) arthroplasty. A protocol of dilute Betadine lavage (0.35%) for 3 minutes was introduced to the practice of the...
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Veröffentlicht in: | The Journal of arthroplasty 2012, Vol.27 (1), p.27-30 |
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creator | Brown, Nicholas M., BS Cipriano, Cara A., MD Moric, Mario, MS Sporer, Scott M., MD Della Valle, Craig J., MD |
description | Abstract This study evaluated the efficacy of a dilute Betadine (Purdue Pharma, Stamford, Conn) lavage in preventing early deep postoperative infection after total hip (THA) and knee (TKA) arthroplasty. A protocol of dilute Betadine lavage (0.35%) for 3 minutes was introduced to the practice of the senior author in June 2008. A total of 1862 consecutive cases (630 THA and 1232 TKA) performed before this were compared with 688 consecutive cases (274 THA and 414 TKA) after for the occurrence of periprosthetic infections within the first 90 days postoperatively. Eighteen early postoperative infections were identified before the use of dilute Betadine lavage, and 1 since (0.97% and 0.15%, respectively; P = .04). There were no significant demographic differences between the 2 groups. Betadine lavage before wound closure may be an inexpensive, effective means of reducing acute postoperative infection after total joint arthroplasty. |
doi_str_mv | 10.1016/j.arth.2011.03.034 |
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A protocol of dilute Betadine lavage (0.35%) for 3 minutes was introduced to the practice of the senior author in June 2008. A total of 1862 consecutive cases (630 THA and 1232 TKA) performed before this were compared with 688 consecutive cases (274 THA and 414 TKA) after for the occurrence of periprosthetic infections within the first 90 days postoperatively. Eighteen early postoperative infections were identified before the use of dilute Betadine lavage, and 1 since (0.97% and 0.15%, respectively; P = .04). There were no significant demographic differences between the 2 groups. Betadine lavage before wound closure may be an inexpensive, effective means of reducing acute postoperative infection after total joint arthroplasty.</description><identifier>ISSN: 0883-5403</identifier><identifier>EISSN: 1532-8406</identifier><identifier>DOI: 10.1016/j.arth.2011.03.034</identifier><identifier>PMID: 21550765</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acute Disease ; Anti-Infective Agents, Local - administration & dosage ; betadine lavage ; Female ; Humans ; Male ; Middle Aged ; Orthopedics ; periprosthetic joint infection ; Povidone-Iodine - administration & dosage ; Prosthesis-Related Infections - prevention & control ; Retrospective Studies ; THA ; Therapeutic Irrigation ; TKA ; Wound Closure Techniques</subject><ispartof>The Journal of arthroplasty, 2012, Vol.27 (1), p.27-30</ispartof><rights>Elsevier Inc.</rights><rights>2012 Elsevier Inc.</rights><rights>Copyright © 2012 Elsevier Inc. 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A protocol of dilute Betadine lavage (0.35%) for 3 minutes was introduced to the practice of the senior author in June 2008. A total of 1862 consecutive cases (630 THA and 1232 TKA) performed before this were compared with 688 consecutive cases (274 THA and 414 TKA) after for the occurrence of periprosthetic infections within the first 90 days postoperatively. Eighteen early postoperative infections were identified before the use of dilute Betadine lavage, and 1 since (0.97% and 0.15%, respectively; P = .04). There were no significant demographic differences between the 2 groups. Betadine lavage before wound closure may be an inexpensive, effective means of reducing acute postoperative infection after total joint arthroplasty.</description><subject>Acute Disease</subject><subject>Anti-Infective Agents, Local - administration & dosage</subject><subject>betadine lavage</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Orthopedics</subject><subject>periprosthetic joint infection</subject><subject>Povidone-Iodine - administration & dosage</subject><subject>Prosthesis-Related Infections - prevention & control</subject><subject>Retrospective Studies</subject><subject>THA</subject><subject>Therapeutic Irrigation</subject><subject>TKA</subject><subject>Wound Closure Techniques</subject><issn>0883-5403</issn><issn>1532-8406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UU1rGzEQFSWlcdP-gR6KbjmtK60-dg2lkNhNmmKooS30JrTaUSx3LTmS1pB_Xy1OeuihMPCY4b1h5j2E3lEyp4TKD7u5jnk7rwmlc8JK8RdoRgWrq5YTeYZmpG1ZJThh5-h1SjtSiELwV-i8LkgaKWYordwwZsDXkHXvPOC1Pur7qbchAl4OIY0FS4PzFvAmwhF8dsHjYPGVmaSbkHI4QNTZHQGvAA54A9EdYplvITuDvwbnM77zFswkfYNeWj0kePuEF-jnzecfyy_V-tvt3fJqXRneyFwJDU1PO66FkR1vKSykqfXCWttpRrqmtcLopnxnO6CkE4wJ1hiwnPdgdN-yC3R52ltOeRghZbV3ycAwaA9hTGpB6YJJ2YjCrE9MU45OEaw6RLfX8VFRoiav1U5NXqvJa0VYKV5E75_Wj90e-r-SZ3ML4eOJAOXJo4OoknHgDfQuFidUH9z_93_6R24G553Rw294hLQLY_TFPkVVqhVR36e0p7ApLUFz-Yv9Adatp1k</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Brown, Nicholas M., BS</creator><creator>Cipriano, Cara A., MD</creator><creator>Moric, Mario, MS</creator><creator>Sporer, Scott M., MD</creator><creator>Della Valle, Craig J., MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2012</creationdate><title>Dilute Betadine Lavage Before Closure for the Prevention of Acute Postoperative Deep Periprosthetic Joint Infection</title><author>Brown, Nicholas M., BS ; Cipriano, Cara A., MD ; Moric, Mario, MS ; Sporer, Scott M., MD ; Della Valle, Craig J., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c476t-5ae7d1b4a5c6b481e96c2a9fffba30b78f5ca7403fbe10b533537cef44decad83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acute Disease</topic><topic>Anti-Infective Agents, Local - administration & dosage</topic><topic>betadine lavage</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Orthopedics</topic><topic>periprosthetic joint infection</topic><topic>Povidone-Iodine - administration & dosage</topic><topic>Prosthesis-Related Infections - prevention & control</topic><topic>Retrospective Studies</topic><topic>THA</topic><topic>Therapeutic Irrigation</topic><topic>TKA</topic><topic>Wound Closure Techniques</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brown, Nicholas M., BS</creatorcontrib><creatorcontrib>Cipriano, Cara A., MD</creatorcontrib><creatorcontrib>Moric, Mario, MS</creatorcontrib><creatorcontrib>Sporer, Scott M., MD</creatorcontrib><creatorcontrib>Della Valle, Craig J., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of arthroplasty</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brown, Nicholas M., BS</au><au>Cipriano, Cara A., MD</au><au>Moric, Mario, MS</au><au>Sporer, Scott M., MD</au><au>Della Valle, Craig J., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dilute Betadine Lavage Before Closure for the Prevention of Acute Postoperative Deep Periprosthetic Joint Infection</atitle><jtitle>The Journal of arthroplasty</jtitle><addtitle>J Arthroplasty</addtitle><date>2012</date><risdate>2012</risdate><volume>27</volume><issue>1</issue><spage>27</spage><epage>30</epage><pages>27-30</pages><issn>0883-5403</issn><eissn>1532-8406</eissn><abstract>Abstract This study evaluated the efficacy of a dilute Betadine (Purdue Pharma, Stamford, Conn) lavage in preventing early deep postoperative infection after total hip (THA) and knee (TKA) arthroplasty. 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subjects | Acute Disease Anti-Infective Agents, Local - administration & dosage betadine lavage Female Humans Male Middle Aged Orthopedics periprosthetic joint infection Povidone-Iodine - administration & dosage Prosthesis-Related Infections - prevention & control Retrospective Studies THA Therapeutic Irrigation TKA Wound Closure Techniques |
title | Dilute Betadine Lavage Before Closure for the Prevention of Acute Postoperative Deep Periprosthetic Joint Infection |
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