Dilute Betadine Lavage Before Closure for the Prevention of Acute Postoperative Deep Periprosthetic Joint Infection

Abstract This study evaluated the efficacy of a dilute Betadine (Purdue Pharma, Stamford, Conn) lavage in preventing early deep postoperative infection after total hip (THA) and knee (TKA) arthroplasty. A protocol of dilute Betadine lavage (0.35%) for 3 minutes was introduced to the practice of the...

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Veröffentlicht in:The Journal of arthroplasty 2012, Vol.27 (1), p.27-30
Hauptverfasser: Brown, Nicholas M., BS, Cipriano, Cara A., MD, Moric, Mario, MS, Sporer, Scott M., MD, Della Valle, Craig J., MD
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container_end_page 30
container_issue 1
container_start_page 27
container_title The Journal of arthroplasty
container_volume 27
creator Brown, Nicholas M., BS
Cipriano, Cara A., MD
Moric, Mario, MS
Sporer, Scott M., MD
Della Valle, Craig J., MD
description Abstract This study evaluated the efficacy of a dilute Betadine (Purdue Pharma, Stamford, Conn) lavage in preventing early deep postoperative infection after total hip (THA) and knee (TKA) arthroplasty. A protocol of dilute Betadine lavage (0.35%) for 3 minutes was introduced to the practice of the senior author in June 2008. A total of 1862 consecutive cases (630 THA and 1232 TKA) performed before this were compared with 688 consecutive cases (274 THA and 414 TKA) after for the occurrence of periprosthetic infections within the first 90 days postoperatively. Eighteen early postoperative infections were identified before the use of dilute Betadine lavage, and 1 since (0.97% and 0.15%, respectively; P = .04). There were no significant demographic differences between the 2 groups. Betadine lavage before wound closure may be an inexpensive, effective means of reducing acute postoperative infection after total joint arthroplasty.
doi_str_mv 10.1016/j.arth.2011.03.034
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Acute Disease
Anti-Infective Agents, Local - administration & dosage
betadine lavage
Female
Humans
Male
Middle Aged
Orthopedics
periprosthetic joint infection
Povidone-Iodine - administration & dosage
Prosthesis-Related Infections - prevention & control
Retrospective Studies
THA
Therapeutic Irrigation
TKA
Wound Closure Techniques
title Dilute Betadine Lavage Before Closure for the Prevention of Acute Postoperative Deep Periprosthetic Joint Infection
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