Detection and quantification of the K103N mutation in HIV reverse transcriptase by pyrosequencing

Abstract Prolonged treatment of human immunodeficiency virus (HIV)–infected patients with nonnucleoside reverse transcriptase inhibitors (NNRTIs) might result in the selection of resistant mutants, the most frequent being the K103N mutation in reverse transcriptase. Resistance mutations are routinel...

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Veröffentlicht in:Diagnostic microbiology and infectious disease 2012, Vol.72 (1), p.90-96
Hauptverfasser: García-González, Cristina, García-Bujalance, Silvia, Ruiz-Carrascoso, Guillermo, Arribas, José Ramón, González-García, Juan, Bernardino, José Ignacio, Pascual-Pareja, José Francisco, Martínez-Prats, Lorena, Delgado, Rafael, Mingorance, Jesús
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Sprache:eng
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