Expression pattern of CK7 and CK20 in nasal polyps, at patients with chronic rhinosinusitis with nasal polyposis
We investigated the expression of cytokeratins 7 (CK7) and 20 (CK20) in nasal polyps on a group of 106 patients with chronic rhinosinusitis with nasal polyposis (45 women - 42% and 61 men - 58%) who benefited from surgical procedures. Harvested biological material was analyzed in the pathology labor...
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| Veröffentlicht in: | Romanian journal of morphology and embryology 2011, Vol.52 (3 Suppl), p.1051-1057 |
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| container_issue | 3 Suppl |
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| container_title | Romanian journal of morphology and embryology |
| container_volume | 52 |
| creator | Mitroi, Mihaela Căpitănescu, Alina Georgescu, Claudia Valentina Mogoantă, Carmen Aurelia Popescu, Camelia Georgescu, Monica Mitroi, G Ioniţă, Elena |
| description | We investigated the expression of cytokeratins 7 (CK7) and 20 (CK20) in nasal polyps on a group of 106 patients with chronic rhinosinusitis with nasal polyposis (45 women - 42% and 61 men - 58%) who benefited from surgical procedures. Harvested biological material was analyzed in the pathology laboratory through two methods: histopathological and immunohistochemical analysis. Classical histopathological method of processing the tissues initially fixed in 10% formalin was used. The tissues were then processed by paraffin impregnation, sectioned and stained with Hematoxylin-Eosin. The immunohistochemical method was based on soluble immunoenzymatic complexes - LSAB/HRP (labeled Streptavidin Biotin) method. We used DAKO LSAB 2 System HRP (Universal DAKO Labeled Streptavidin Biotin 2 System Horseradish Peroxidase). The expressions of CK7 and CK20 in nasal polyps were analyzed. |
| format | Article |
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| ispartof | Romanian journal of morphology and embryology, 2011, Vol.52 (3 Suppl), p.1051-1057 |
| issn | 1220-0522 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Chronic Disease Female Humans Hypersensitivity - metabolism Hypersensitivity - pathology Immunohistochemistry Inflammation - complications Inflammation - pathology Keratin-20 - metabolism Keratin-7 - metabolism Male Middle Aged Nasal Polyps - complications Nasal Polyps - metabolism Nasal Polyps - pathology Sinusitis - complications Sinusitis - metabolism Sinusitis - pathology |
| title | Expression pattern of CK7 and CK20 in nasal polyps, at patients with chronic rhinosinusitis with nasal polyposis |
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