Analyses of the genotoxic and mutagenic potential of the products formed after the biotransformation of the azo dye Disperse Red 1

► Azo dyes constitute the largest class of synthetic dyes. ► The oxidation and reduction products of the azo dye Disperse Red 1 were identified. ► These products formed showed mutagenic potential in the Salmonella assay. ► The discharge of this dye into water bodies may represent human and ecologica...

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Veröffentlicht in:	Toxicology in vitro 2011-12, Vol.25 (8), p.2054-2063
Hauptverfasser:	Chequer, Farah Maria Drumond, Lizier, Thiago Mescoloto, de Felício, Rafael, Zanoni, Maria Valnice Boldrin, Debonsi, Hosana Maria, Lopes, Norberto Peporine, Marcos, Ricard, de Oliveira, Danielle Palma
Format:	Artikel
Sprache:	eng
Schlagworte:	Ames test Animals Aromatics Azo Compounds - chemistry Azo Compounds - metabolism Azo Compounds - toxicity Azo dye Biotransformation Cell Line, Tumor Chromatography, High Pressure Liquid Coloring Agents - chemistry Coloring Agents - metabolism Coloring Agents - toxicity Disperse Red 1 Electrolysis Gas Chromatography-Mass Spectrometry Mice Mouse lymphoma assay Mutagenicity Mutagenicity Tests Mutagens - chemistry Mutagens - metabolism Mutagens - toxicity Oxidation-Reduction Salmonella Salmonella typhimurium - drug effects Salmonella typhimurium - genetics
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