Modulation of the heterogeneous senescence of human mesenchymal stem cells on chemically-modified surfaces

[Display omitted] ► The heterogeneous aging of hMSC was examined on chemically defined self-assembly monolayer surfaces. ► Surface energy was shown to regulate aged hMSC morphology, survival, and proteoglycan expression. ► High surface energy supplied a preferable environment for hMSC survival and e...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2012-02, Vol.90, p.36-40
Hauptverfasser:	Kim, Sung Hoon, Lee, Byung Man, Min, Seul Ki, Song, Sun U., Cho, Jeong Ho, Cho, Kilwon, Shin, Hwa Sung
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Biocompatible Materials - chemistry Biocompatible Materials - metabolism Cell Count Cell Differentiation - physiology Cell Proliferation Cell Survival Cells, Cultured Cellular Senescence Glass - chemistry Human mesenchymal stem cell Humans Hydrophobic and Hydrophilic Interactions Immunoassay Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - physiology Microscopy, Phase-Contrast Morphology Proteoglycan Proteoglycans - analysis Proteoglycans - biosynthesis Self-assembly monolayer Silanes - chemistry Silanes - metabolism Surface energy Surface Properties Survival Tissue Engineering - methods Tissue Scaffolds
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