Personalized Medicine: Progress and Promise
Personalized medicine is a broad and rapidly advancing field of health care that is informed by each person's unique clinical, genetic, genomic, and environmental information. Personalized medicine depends on multidisciplinary health care teams and integrated technologies (e.g., clinical decisi...
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| Veröffentlicht in: | Annual review of genomics and human genetics 2011-01, Vol.12 (1), p.217-244 |
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| container_title | Annual review of genomics and human genetics |
| container_volume | 12 |
| creator | Chan, Isaac S Ginsburg, Geoffrey S |
| description | Personalized medicine is a broad and rapidly advancing field of health care that is informed by each person's unique clinical, genetic, genomic, and environmental information. Personalized medicine depends on multidisciplinary health care teams and integrated technologies (e.g., clinical decision support) to utilize our molecular understanding of disease in order to optimize preventive health care strategies. Human genome information now allows providers to create optimized care plans at every stage of a disease, shifting the focus from reactive to preventive health care. The further integration of personalized medicine into the clinical workflow requires overcoming several barriers in education, accessibility, regulation, and reimbursement. This review focuses on providing a comprehensive understanding of personalized medicine, from scientific discovery at the laboratory bench to integration of these novel ways of understanding human biology at the bedside. |
| doi_str_mv | 10.1146/annurev-genom-082410-101446 |
| format | Article |
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This review focuses on providing a comprehensive understanding of personalized medicine, from scientific discovery at the laboratory bench to integration of these novel ways of understanding human biology at the bedside.</description><subject>clinical decision support</subject><subject>comparative effectiveness research</subject><subject>Disease - genetics</subject><subject>Genetic Predisposition to Disease</subject><subject>Genome, Human</subject><subject>genomic medicine</subject><subject>Humans</subject><subject>Pharmacogenetics</subject><subject>pharmacogenomics</subject><subject>Precision Medicine</subject><subject>Preventive Medicine</subject><subject>translational medicine</subject><issn>1527-8204</issn><issn>1545-293X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkE1LxDAQhoMorq7-BVnw4EGqM2mapnpRFr9gxT0oeAtpOl0q_ViTraK_3tauXsXTJPDM-w4PY4cIJ4hCnpq6bh29BQuqmyoAxQVCgIBCyA22g5GIAp6Ez5v9m8eB4iBGbNf7FwBQSsA2G3GMOSZhssOO5-R8U5uy-KRsck9ZYYuaziZz1ywceT8xddZ_qsLTHtvKTelpfz3H7On66nF6G8webu6ml7PAiDhaBXFmVS6EzY0KQ1TShiIBqfJImtRKkRlITcSjPOKWUGJIICxmqQGQYLoZjtnRkLt0zWtLfqW7dktlaWpqWq8TRJSh4PAnqVR3glLYk-cDaV3jvaNcL11RGfehEXSvVa-16m-tetCqB63d9sG6p00ryn53fzx2wMUA9Cmm7HIKevf_6vgCkDuM4w</recordid><startdate>20110101</startdate><enddate>20110101</enddate><creator>Chan, Isaac S</creator><creator>Ginsburg, Geoffrey S</creator><general>Annual Reviews</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>20110101</creationdate><title>Personalized Medicine: Progress and Promise</title><author>Chan, Isaac S ; Ginsburg, Geoffrey S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a475t-7dc8f44cfa833186c349068f56abc64da0ba525f52ce1613e04c1dba0060adba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>clinical decision support</topic><topic>comparative effectiveness research</topic><topic>Disease - genetics</topic><topic>Genetic Predisposition to Disease</topic><topic>Genome, Human</topic><topic>genomic medicine</topic><topic>Humans</topic><topic>Pharmacogenetics</topic><topic>pharmacogenomics</topic><topic>Precision Medicine</topic><topic>Preventive Medicine</topic><topic>translational medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan, Isaac S</creatorcontrib><creatorcontrib>Ginsburg, Geoffrey S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Annual review of genomics and human genetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, Isaac S</au><au>Ginsburg, Geoffrey S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Personalized Medicine: Progress and Promise</atitle><jtitle>Annual review of genomics and human genetics</jtitle><addtitle>Annu Rev Genomics Hum Genet</addtitle><date>2011-01-01</date><risdate>2011</risdate><volume>12</volume><issue>1</issue><spage>217</spage><epage>244</epage><pages>217-244</pages><issn>1527-8204</issn><eissn>1545-293X</eissn><abstract>Personalized medicine is a broad and rapidly advancing field of health care that is informed by each person's unique clinical, genetic, genomic, and environmental information. 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| ispartof | Annual review of genomics and human genetics, 2011-01, Vol.12 (1), p.217-244 |
| issn | 1527-8204 1545-293X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_911163420 |
| source | Annual Reviews Complete A-Z List; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | clinical decision support comparative effectiveness research Disease - genetics Genetic Predisposition to Disease Genome, Human genomic medicine Humans Pharmacogenetics pharmacogenomics Precision Medicine Preventive Medicine translational medicine |
| title | Personalized Medicine: Progress and Promise |
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