Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2011-08, Vol.55 (8), p.3889-3898 |
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| creator | VILCHEZE, Catherine BAUGHN, Anthony D TUFARIELLO, Joann LEUNG, Lawrence W KUO, Mack BASLER, Christopher F ALLAND, David SACCHETTINI, James C FREUNDLICH, Joel S JACOBS, William R |
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| doi_str_mv | 10.1128/AAC.00266-11 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.00266-11</identifier><identifier>PMID: 21628538</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Aerobiosis ; Anaerobiosis ; Animals ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antitubercular Agents ; Antitubercular Agents - chemistry ; Antitubercular Agents - pharmacology ; Bacterial Proteins ; Bacterial Proteins - antagonists & inhibitors ; Bacterial Proteins - metabolism ; Biological and medical sciences ; Catalase - metabolism ; Cells, Cultured ; Drug Design ; Drug Resistance, Multiple, Bacterial ; Fatty Acid Synthase, Type I - antagonists & inhibitors ; Macrophages - drug effects ; Macrophages - microbiology ; Medical sciences ; Mice ; Mice, Inbred C57BL ; Microbial Sensitivity Tests ; Mycobacterium tuberculosis ; Mycobacterium tuberculosis - drug effects ; Oxidoreductases ; Oxidoreductases - antagonists & inhibitors ; Pharmacology. Drug treatments ; Plasmodium falciparum ; Plasmodium falciparum - drug effects ; Plasmodium falciparum - enzymology ; Stearic Acids - metabolism ; Structure-Activity Relationship ; Susceptibility ; Tuberculosis, Multidrug-Resistant - microbiology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2011-08, Vol.55 (8), p.3889-3898</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011, American Society for Microbiology. All Rights Reserved.</rights><rights>Copyright © 2011, American Society for Microbiology. All Rights Reserved. 2011 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a548t-a39483e77cca556cca52eac352ad5fbbcecc22554e24a458d200d868383b9ade3</citedby><cites>FETCH-LOGICAL-a548t-a39483e77cca556cca52eac352ad5fbbcecc22554e24a458d200d868383b9ade3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147652/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147652/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24419742$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21628538$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VILCHEZE, Catherine</creatorcontrib><creatorcontrib>BAUGHN, Anthony D</creatorcontrib><creatorcontrib>TUFARIELLO, Joann</creatorcontrib><creatorcontrib>LEUNG, Lawrence W</creatorcontrib><creatorcontrib>KUO, Mack</creatorcontrib><creatorcontrib>BASLER, Christopher F</creatorcontrib><creatorcontrib>ALLAND, David</creatorcontrib><creatorcontrib>SACCHETTINI, James C</creatorcontrib><creatorcontrib>FREUNDLICH, Joel S</creatorcontrib><creatorcontrib>JACOBS, William R</creatorcontrib><title>Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Aerobiosis</subject><subject>Anaerobiosis</subject><subject>Animals</subject><subject>Antibiotics. Antiinfectious agents. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antitubercular Agents</topic><topic>Antitubercular Agents - chemistry</topic><topic>Antitubercular Agents - pharmacology</topic><topic>Bacterial Proteins</topic><topic>Bacterial Proteins - antagonists & inhibitors</topic><topic>Bacterial Proteins - metabolism</topic><topic>Biological and medical sciences</topic><topic>Catalase - metabolism</topic><topic>Cells, Cultured</topic><topic>Drug Design</topic><topic>Drug Resistance, Multiple, Bacterial</topic><topic>Fatty Acid Synthase, Type I - antagonists & inhibitors</topic><topic>Macrophages - drug effects</topic><topic>Macrophages - microbiology</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>Microbial Sensitivity Tests</topic><topic>Mycobacterium tuberculosis</topic><topic>Mycobacterium tuberculosis - drug effects</topic><topic>Oxidoreductases</topic><topic>Oxidoreductases - antagonists & inhibitors</topic><topic>Pharmacology. Drug treatments</topic><topic>Plasmodium falciparum</topic><topic>Plasmodium falciparum - drug effects</topic><topic>Plasmodium falciparum - enzymology</topic><topic>Stearic Acids - metabolism</topic><topic>Structure-Activity Relationship</topic><topic>Susceptibility</topic><topic>Tuberculosis, Multidrug-Resistant - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>VILCHEZE, Catherine</creatorcontrib><creatorcontrib>BAUGHN, Anthony D</creatorcontrib><creatorcontrib>TUFARIELLO, Joann</creatorcontrib><creatorcontrib>LEUNG, Lawrence W</creatorcontrib><creatorcontrib>KUO, Mack</creatorcontrib><creatorcontrib>BASLER, Christopher F</creatorcontrib><creatorcontrib>ALLAND, David</creatorcontrib><creatorcontrib>SACCHETTINI, James C</creatorcontrib><creatorcontrib>FREUNDLICH, Joel S</creatorcontrib><creatorcontrib>JACOBS, William R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>VILCHEZE, Catherine</au><au>BAUGHN, Anthony D</au><au>TUFARIELLO, Joann</au><au>LEUNG, Lawrence W</au><au>KUO, Mack</au><au>BASLER, Christopher F</au><au>ALLAND, David</au><au>SACCHETTINI, James C</au><au>FREUNDLICH, Joel S</au><au>JACOBS, William R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>Antimicrob Agents Chemother</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2011-08-01</date><risdate>2011</risdate><volume>55</volume><issue>8</issue><spage>3889</spage><epage>3898</epage><pages>3889-3898</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>21628538</pmid><doi>10.1128/AAC.00266-11</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Aerobiosis Anaerobiosis Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antitubercular Agents Antitubercular Agents - chemistry Antitubercular Agents - pharmacology Bacterial Proteins Bacterial Proteins - antagonists & inhibitors Bacterial Proteins - metabolism Biological and medical sciences Catalase - metabolism Cells, Cultured Drug Design Drug Resistance, Multiple, Bacterial Fatty Acid Synthase, Type I - antagonists & inhibitors Macrophages - drug effects Macrophages - microbiology Medical sciences Mice Mice, Inbred C57BL Microbial Sensitivity Tests Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Oxidoreductases Oxidoreductases - antagonists & inhibitors Pharmacology. Drug treatments Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium falciparum - enzymology Stearic Acids - metabolism Structure-Activity Relationship Susceptibility Tuberculosis, Multidrug-Resistant - microbiology |
| title | Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions |
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