A novel approach using telomerase-specific replication-selective adenovirus for detection of circulating tumor cells in breast cancer patients

The aim of this study was to develop a new method for detecting circulating tumor cells (CTCs) in breast cancer patients by using the telomerase-specific replication-selective adenovirus OBP-401. Once transfected, OBP-401 can replicate only in telomerase expressing cells and emit fluorescence as it...

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Veröffentlicht in:	Breast cancer research and treatment 2011-08, Vol.128 (3), p.765-773
Hauptverfasser:	Kim, Seung Jin, Masago, Akinori, Tamaki, Yasuhiro, Akazawa, Kenji, Tsukamoto, Fumine, Sato, Jun, Ozawa, Toshiyuki, Tsujino, Yukio, Noguchi, Shinzaburo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Adenovirus Adenoviruses Adult Biological and medical sciences Biomarkers, Tumor - metabolism Breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer research Cancer therapies Cell Line, Tumor Cells Clinical Trial Diagnostic tests Diagnostic Tests, Routine - methods Female Gynecology. Andrology. Obstetrics Humans Male Mammary gland diseases Medical sciences Medicine Medicine & Public Health Middle Aged Neoplasm Metastasis Neoplastic Cells, Circulating - pathology Oncology Receptors, Estrogen - metabolism Reference Values Telomerase Tumors Young Adult
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