Combinatorial Effect of Two Framework Mutations (E119V and I222L) in the Neuraminidase Active Site of H3N2 Influenza Virus on Resistance to Oseltamivir

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2011-06, Vol.55 (6), p.2942-2952
Hauptverfasser:	RICHARD, Mathilde, FERRARIS, Olivier, ERNY, Alexandra, BARTHELEMY, Mendy, TRAVERSIER, Aurélien, SABATIER, Murielle, HAY, Alan, LIN, Yi Pu, RUSSELL, Rupert J, LINA, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - pharmacology Binding Sites Biological and medical sciences Cells, Cultured Dogs Drug Resistance, Viral Influenza A Virus, H3N2 Subtype Influenza A Virus, H3N2 Subtype - drug effects Influenza A Virus, H3N2 Subtype - enzymology Influenza A Virus, H3N2 Subtype - genetics Influenza A Virus, H3N2 Subtype - growth & development Influenza virus Medical sciences Mutation Neuraminidase Neuraminidase - antagonists & inhibitors Neuraminidase - genetics Neuraminidase - metabolism Oseltamivir Oseltamivir - pharmacology Pharmacology. Drug treatments Virion - enzymology
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