Combinatorial Effect of Two Framework Mutations (E119V and I222L) in the Neuraminidase Active Site of H3N2 Influenza Virus on Resistance to Oseltamivir
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2011-06, Vol.55 (6), p.2942-2952 |
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| container_title | Antimicrobial Agents and Chemotherapy |
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| creator | RICHARD, Mathilde FERRARIS, Olivier ERNY, Alexandra BARTHELEMY, Mendy TRAVERSIER, Aurélien SABATIER, Murielle HAY, Alan LIN, Yi Pu RUSSELL, Rupert J LINA, Bruno |
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| doi_str_mv | 10.1128/AAC.01699-10 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.01699-10</identifier><identifier>PMID: 21422222</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Animals ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - pharmacology ; Binding Sites ; Biological and medical sciences ; Cells, Cultured ; Dogs ; Drug Resistance, Viral ; Influenza A Virus, H3N2 Subtype ; Influenza A Virus, H3N2 Subtype - drug effects ; Influenza A Virus, H3N2 Subtype - enzymology ; Influenza A Virus, H3N2 Subtype - genetics ; Influenza A Virus, H3N2 Subtype - growth & development ; Influenza virus ; Medical sciences ; Mutation ; Neuraminidase ; Neuraminidase - antagonists & inhibitors ; Neuraminidase - genetics ; Neuraminidase - metabolism ; Oseltamivir ; Oseltamivir - pharmacology ; Pharmacology. Drug treatments ; Virion - enzymology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2942-2952</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011, American Society for Microbiology</rights><rights>Copyright © 2011, American Society for Microbiology 2011 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a505t-2f288b46cd7c3a15a58d1f87c543a8bf6d12df504641dc31189b3ba6ff54bb7d3</citedby><cites>FETCH-LOGICAL-a505t-2f288b46cd7c3a15a58d1f87c543a8bf6d12df504641dc31189b3ba6ff54bb7d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101467/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101467/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24242484$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21422222$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RICHARD, Mathilde</creatorcontrib><creatorcontrib>FERRARIS, Olivier</creatorcontrib><creatorcontrib>ERNY, Alexandra</creatorcontrib><creatorcontrib>BARTHELEMY, Mendy</creatorcontrib><creatorcontrib>TRAVERSIER, Aurélien</creatorcontrib><creatorcontrib>SABATIER, Murielle</creatorcontrib><creatorcontrib>HAY, Alan</creatorcontrib><creatorcontrib>LIN, Yi Pu</creatorcontrib><creatorcontrib>RUSSELL, Rupert J</creatorcontrib><creatorcontrib>LINA, Bruno</creatorcontrib><title>Combinatorial Effect of Two Framework Mutations (E119V and I222L) in the Neuraminidase Active Site of H3N2 Influenza Virus on Resistance to Oseltamivir</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Animals</subject><subject>Antibiotics. Antiinfectious agents. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antiviral Agents</topic><topic>Antiviral Agents - pharmacology</topic><topic>Binding Sites</topic><topic>Biological and medical sciences</topic><topic>Cells, Cultured</topic><topic>Dogs</topic><topic>Drug Resistance, Viral</topic><topic>Influenza A Virus, H3N2 Subtype</topic><topic>Influenza A Virus, H3N2 Subtype - drug effects</topic><topic>Influenza A Virus, H3N2 Subtype - enzymology</topic><topic>Influenza A Virus, H3N2 Subtype - genetics</topic><topic>Influenza A Virus, H3N2 Subtype - growth & development</topic><topic>Influenza virus</topic><topic>Medical sciences</topic><topic>Mutation</topic><topic>Neuraminidase</topic><topic>Neuraminidase - antagonists & inhibitors</topic><topic>Neuraminidase - genetics</topic><topic>Neuraminidase - metabolism</topic><topic>Oseltamivir</topic><topic>Oseltamivir - pharmacology</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>21422222</pmid><doi>10.1128/AAC.01699-10</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2942-2952 |
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| source | MEDLINE; PubMed Central; EZB Electronic Journals Library |
| subjects | Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - pharmacology Binding Sites Biological and medical sciences Cells, Cultured Dogs Drug Resistance, Viral Influenza A Virus, H3N2 Subtype Influenza A Virus, H3N2 Subtype - drug effects Influenza A Virus, H3N2 Subtype - enzymology Influenza A Virus, H3N2 Subtype - genetics Influenza A Virus, H3N2 Subtype - growth & development Influenza virus Medical sciences Mutation Neuraminidase Neuraminidase - antagonists & inhibitors Neuraminidase - genetics Neuraminidase - metabolism Oseltamivir Oseltamivir - pharmacology Pharmacology. Drug treatments Virion - enzymology |
| title | Combinatorial Effect of Two Framework Mutations (E119V and I222L) in the Neuraminidase Active Site of H3N2 Influenza Virus on Resistance to Oseltamivir |
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