Heligmosomoides polygyrus elicits a dominant nonprotective antibody response directed against restricted glycan and peptide epitopes

Heligmosomoides polygyrus is a widely used gastrointestinal helminth model of long-term chronic infection in mice, which has not been well-characterized at the antigenic level. We now identify the major targets of the murine primary Ab response as a subset of the secreted products in H. polygyrus ex...

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Veröffentlicht in:The Journal of immunology (1950) 2011-11, Vol.187 (9), p.4764-4777
Hauptverfasser: Hewitson, James P, Filbey, Kara J, Grainger, John R, Dowle, Adam A, Pearson, Mark, Murray, Janice, Harcus, Yvonne, Maizels, Rick M
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Sprache:eng
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