GLP‐2 receptor expression in excitatory and inhibitory enteric neurons and its role in mouse duodenum contractility

Background Glucagon‐like peptide 2 (GLP‐2), a nutrient‐responsive hormone, exerts various actions in the gastrointestinal tract that are mediated by a G‐protein coupled receptor called GLP‐2R. A little information is available on GLP‐2R expression in enteric neurons and nothing on the interstitial...

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Veröffentlicht in:	Neurogastroenterology and motility 2011-09, Vol.23 (9), p.e383-e392
Hauptverfasser:	Cinci, L., Faussone‐Pellegrini, M. S., Rotondo, A., Mulè, F., Vannucchi, M. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Duodenum Duodenum - cytology Duodenum - innervation Duodenum - physiology Enteric nervous system Enteric Nervous System - cytology enteric neurons excitatory neurotransmitters G protein-coupled receptors Gastrointestinal tract Glucagon-like peptide 2 Glucagon-Like Peptide 2 - metabolism Glucagon-Like Peptide-2 Receptor glucagon‐like hormones Hormones Humans Immunohistochemistry inhibitory neurotransmitters Interstitial Cells of Cajal - cytology Interstitial Cells of Cajal - metabolism intestinal motility Male Mice Mice, Inbred C57BL Muscle contraction Muscle Contraction - physiology Muscle, Smooth - innervation Muscle, Smooth - physiology Muscles myenteric plexus Nerves Nervous system Neurons Neurons - physiology Neurotransmission Neurotransmitter Agents - metabolism Neurotransmitters Nitric oxide Receptors, Glucagon - metabolism Vasoactive intestinal peptide
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