Cross-national clinical and functional remission rates: Worldwide Schizophrenia Outpatient Health Outcomes (W-SOHO) study
Evidence suggests that schizophrenia may have a better outcome for individuals living in low- and middle-income countries compared with affluent settings. To determine the frequency of symptom and functional remission in out-patients with schizophrenia in different regions of the world. Using data f...
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| Veröffentlicht in: | British journal of psychiatry 2011-09, Vol.199 (3), p.194-201 |
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| creator | Haro, Josep Maria Novick, Diego Bertsch, Jordan Karagianis, Jamie Dossenbach, Martin Jones, Peter B |
| description | Evidence suggests that schizophrenia may have a better outcome for individuals living in low- and middle-income countries compared with affluent settings.
To determine the frequency of symptom and functional remission in out-patients with schizophrenia in different regions of the world.
Using data from the Worldwide-Schizophrenia Outpatient Health Outcomes (W-SOHO) study we measured clinical and functional remission in out-patients with schizophrenia in different regions of the world, and examined sociodemographic and clinical factors associated with these outcomes. The 11 078 participants analysed from 37 participating countries were grouped into 6 regions: South Europe, North Europe, Central and Eastern Europe, Latin America, North Africa and Middle East, and East Asia.
In total, 66.1% achieved clinical remission during the 3-year follow-up (range: 60.1% in North Europe to 84.4% in East Asia) and 25.4% achieved functional remission (range: 17.8% in North Africa and Middle East to 35.0% in North Europe). Regional differences were not explained by participants' clinical characteristics. Baseline social functioning, being female and previously untreated were consistent predictors of remission across regions.
Clinical outcomes of schizophrenia seem to be worse in Europe compared with other regions. However, functional remission follows a different pattern. |
| doi_str_mv | 10.1192/bjp.bp.110.082065 |
| format | Article |
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To determine the frequency of symptom and functional remission in out-patients with schizophrenia in different regions of the world.
Using data from the Worldwide-Schizophrenia Outpatient Health Outcomes (W-SOHO) study we measured clinical and functional remission in out-patients with schizophrenia in different regions of the world, and examined sociodemographic and clinical factors associated with these outcomes. The 11 078 participants analysed from 37 participating countries were grouped into 6 regions: South Europe, North Europe, Central and Eastern Europe, Latin America, North Africa and Middle East, and East Asia.
In total, 66.1% achieved clinical remission during the 3-year follow-up (range: 60.1% in North Europe to 84.4% in East Asia) and 25.4% achieved functional remission (range: 17.8% in North Africa and Middle East to 35.0% in North Europe). Regional differences were not explained by participants' clinical characteristics. Baseline social functioning, being female and previously untreated were consistent predictors of remission across regions.
Clinical outcomes of schizophrenia seem to be worse in Europe compared with other regions. However, functional remission follows a different pattern.</description><identifier>ISSN: 0007-1250</identifier><identifier>EISSN: 1472-1465</identifier><identifier>DOI: 10.1192/bjp.bp.110.082065</identifier><identifier>PMID: 21881098</identifier><identifier>CODEN: BJPYAJ</identifier><language>eng</language><publisher>England: Cambridge University Press</publisher><subject>Adult ; Africa, Northern - epidemiology ; Antipsychotic Agents - therapeutic use ; Benzodiazepines - therapeutic use ; Clinical outcomes ; Comparative studies ; Consultants ; Cross-Cultural Comparison ; East Asia ; Europe ; Europe - epidemiology ; Far East - epidemiology ; Female ; Health status ; Humans ; Latin America - epidemiology ; Logistic Models ; Low income groups ; Male ; Mental disorders ; Middle East - epidemiology ; North Africa ; Outcome Assessment (Health Care) - statistics & numerical data ; Patients ; Prognosis ; Prospective Studies ; Psychiatrists ; Psychiatry ; Psychotropic drugs ; Regional variations ; Remission ; Remission (Medicine) ; Remission Induction ; Schizophrenia ; Schizophrenia - drug therapy ; Schizophrenia - epidemiology ; Schizophrenic Psychology ; Severity of Illness Index ; Sex Factors ; Social functioning ; Sociodemographics ; Socioeconomic Factors ; Substance-Related Disorders - epidemiology ; Suicide, Attempted - statistics & numerical data</subject><ispartof>British journal of psychiatry, 2011-09, Vol.199 (3), p.194-201</ispartof><rights>Copyright © Royal College of Psychiatrists, 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c501t-2f028e3451caf14e19b73beb5bb938148139658fb7e5c92dc9894359569782b23</citedby><cites>FETCH-LOGICAL-c501t-2f028e3451caf14e19b73beb5bb938148139658fb7e5c92dc9894359569782b23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,12825,27901,27902,30976,30977</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21881098$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Haro, Josep Maria</creatorcontrib><creatorcontrib>Novick, Diego</creatorcontrib><creatorcontrib>Bertsch, Jordan</creatorcontrib><creatorcontrib>Karagianis, Jamie</creatorcontrib><creatorcontrib>Dossenbach, Martin</creatorcontrib><creatorcontrib>Jones, Peter B</creatorcontrib><title>Cross-national clinical and functional remission rates: Worldwide Schizophrenia Outpatient Health Outcomes (W-SOHO) study</title><title>British journal of psychiatry</title><addtitle>Br J Psychiatry</addtitle><description>Evidence suggests that schizophrenia may have a better outcome for individuals living in low- and middle-income countries compared with affluent settings.
To determine the frequency of symptom and functional remission in out-patients with schizophrenia in different regions of the world.
Using data from the Worldwide-Schizophrenia Outpatient Health Outcomes (W-SOHO) study we measured clinical and functional remission in out-patients with schizophrenia in different regions of the world, and examined sociodemographic and clinical factors associated with these outcomes. The 11 078 participants analysed from 37 participating countries were grouped into 6 regions: South Europe, North Europe, Central and Eastern Europe, Latin America, North Africa and Middle East, and East Asia.
In total, 66.1% achieved clinical remission during the 3-year follow-up (range: 60.1% in North Europe to 84.4% in East Asia) and 25.4% achieved functional remission (range: 17.8% in North Africa and Middle East to 35.0% in North Europe). Regional differences were not explained by participants' clinical characteristics. Baseline social functioning, being female and previously untreated were consistent predictors of remission across regions.
Clinical outcomes of schizophrenia seem to be worse in Europe compared with other regions. However, functional remission follows a different pattern.</description><subject>Adult</subject><subject>Africa, Northern - epidemiology</subject><subject>Antipsychotic Agents - therapeutic use</subject><subject>Benzodiazepines - therapeutic use</subject><subject>Clinical outcomes</subject><subject>Comparative studies</subject><subject>Consultants</subject><subject>Cross-Cultural Comparison</subject><subject>East Asia</subject><subject>Europe</subject><subject>Europe - epidemiology</subject><subject>Far East - epidemiology</subject><subject>Female</subject><subject>Health status</subject><subject>Humans</subject><subject>Latin America - epidemiology</subject><subject>Logistic Models</subject><subject>Low income groups</subject><subject>Male</subject><subject>Mental disorders</subject><subject>Middle East - epidemiology</subject><subject>North Africa</subject><subject>Outcome Assessment (Health Care) - statistics & numerical data</subject><subject>Patients</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Psychiatrists</subject><subject>Psychiatry</subject><subject>Psychotropic drugs</subject><subject>Regional variations</subject><subject>Remission</subject><subject>Remission (Medicine)</subject><subject>Remission Induction</subject><subject>Schizophrenia</subject><subject>Schizophrenia - drug therapy</subject><subject>Schizophrenia - epidemiology</subject><subject>Schizophrenic Psychology</subject><subject>Severity of Illness Index</subject><subject>Sex Factors</subject><subject>Social functioning</subject><subject>Sociodemographics</subject><subject>Socioeconomic Factors</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Suicide, Attempted - statistics & numerical data</subject><issn>0007-1250</issn><issn>1472-1465</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkUFv0zAYhi3ExMrgB3BBljgwDum-z45jezdUDTppUg8b2tGyHUdNlSbBToTKr8dVCwcuO_n1p-d7Jfsh5APCElGzG7cbl27MGZagGFTiFVlgKVmBZSVekwUAyAKZgEvyNqVdvvKSyTfkkqFSCFotyGEVh5SK3k7t0NuO-q7tW5-D7WvazL0_z2PYtynlTKOdQrqlz0Ps6l9tHeij37a_h3EbQ99aupmnMZeFfqLrYLtpe5z4YR8SvX4uHjfrzReaprk-vCMXje1SeH8-r8iPb3dPq3XxsPl-v_r6UHgBOBWsAaYCLwV622AZUDvJXXDCOc0Vlgq5roRqnAzCa1Z7rXTJhRaVloo5xq_I51PvGIefc0iTyS_xoetsH4Y5GY1QVZUA_TIJDLQE8TKplBQglIZMfvqP3A1zzD-aDOMoKqY1ykzhifJHGzE0Zozt3saDQTBH1SarNm7MGcxJdd75eG6e3T7U_zb-uuV_AOL0pLw</recordid><startdate>20110901</startdate><enddate>20110901</enddate><creator>Haro, Josep Maria</creator><creator>Novick, Diego</creator><creator>Bertsch, Jordan</creator><creator>Karagianis, Jamie</creator><creator>Dossenbach, Martin</creator><creator>Jones, Peter B</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7TK</scope><scope>7XB</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>M2M</scope><scope>M2O</scope><scope>M2R</scope><scope>M2S</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20110901</creationdate><title>Cross-national clinical and functional remission rates: Worldwide Schizophrenia Outpatient Health Outcomes (W-SOHO) study</title><author>Haro, Josep Maria ; Novick, Diego ; Bertsch, Jordan ; Karagianis, Jamie ; Dossenbach, Martin ; Jones, Peter B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c501t-2f028e3451caf14e19b73beb5bb938148139658fb7e5c92dc9894359569782b23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Africa, Northern - 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drug therapy</topic><topic>Schizophrenia - epidemiology</topic><topic>Schizophrenic Psychology</topic><topic>Severity of Illness Index</topic><topic>Sex Factors</topic><topic>Social functioning</topic><topic>Sociodemographics</topic><topic>Socioeconomic Factors</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Suicide, Attempted - statistics & numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Haro, Josep Maria</creatorcontrib><creatorcontrib>Novick, Diego</creatorcontrib><creatorcontrib>Bertsch, Jordan</creatorcontrib><creatorcontrib>Karagianis, Jamie</creatorcontrib><creatorcontrib>Dossenbach, Martin</creatorcontrib><creatorcontrib>Jones, Peter B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Sociology Collection</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Haro, Josep Maria</au><au>Novick, Diego</au><au>Bertsch, Jordan</au><au>Karagianis, Jamie</au><au>Dossenbach, Martin</au><au>Jones, Peter B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cross-national clinical and functional remission rates: Worldwide Schizophrenia Outpatient Health Outcomes (W-SOHO) study</atitle><jtitle>British journal of psychiatry</jtitle><addtitle>Br J Psychiatry</addtitle><date>2011-09-01</date><risdate>2011</risdate><volume>199</volume><issue>3</issue><spage>194</spage><epage>201</epage><pages>194-201</pages><issn>0007-1250</issn><eissn>1472-1465</eissn><coden>BJPYAJ</coden><abstract>Evidence suggests that schizophrenia may have a better outcome for individuals living in low- and middle-income countries compared with affluent settings.
To determine the frequency of symptom and functional remission in out-patients with schizophrenia in different regions of the world.
Using data from the Worldwide-Schizophrenia Outpatient Health Outcomes (W-SOHO) study we measured clinical and functional remission in out-patients with schizophrenia in different regions of the world, and examined sociodemographic and clinical factors associated with these outcomes. The 11 078 participants analysed from 37 participating countries were grouped into 6 regions: South Europe, North Europe, Central and Eastern Europe, Latin America, North Africa and Middle East, and East Asia.
In total, 66.1% achieved clinical remission during the 3-year follow-up (range: 60.1% in North Europe to 84.4% in East Asia) and 25.4% achieved functional remission (range: 17.8% in North Africa and Middle East to 35.0% in North Europe). Regional differences were not explained by participants' clinical characteristics. Baseline social functioning, being female and previously untreated were consistent predictors of remission across regions.
Clinical outcomes of schizophrenia seem to be worse in Europe compared with other regions. However, functional remission follows a different pattern.</abstract><cop>England</cop><pub>Cambridge University Press</pub><pmid>21881098</pmid><doi>10.1192/bjp.bp.110.082065</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | British journal of psychiatry, 2011-09, Vol.199 (3), p.194-201 |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection; Cambridge University Press Journals Complete |
| subjects | Adult Africa, Northern - epidemiology Antipsychotic Agents - therapeutic use Benzodiazepines - therapeutic use Clinical outcomes Comparative studies Consultants Cross-Cultural Comparison East Asia Europe Europe - epidemiology Far East - epidemiology Female Health status Humans Latin America - epidemiology Logistic Models Low income groups Male Mental disorders Middle East - epidemiology North Africa Outcome Assessment (Health Care) - statistics & numerical data Patients Prognosis Prospective Studies Psychiatrists Psychiatry Psychotropic drugs Regional variations Remission Remission (Medicine) Remission Induction Schizophrenia Schizophrenia - drug therapy Schizophrenia - epidemiology Schizophrenic Psychology Severity of Illness Index Sex Factors Social functioning Sociodemographics Socioeconomic Factors Substance-Related Disorders - epidemiology Suicide, Attempted - statistics & numerical data |
| title | Cross-national clinical and functional remission rates: Worldwide Schizophrenia Outpatient Health Outcomes (W-SOHO) study |
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