Hemocompatibility of a hydrodynamic levitation centrifugal blood pump
A noncontact type centrifugal pump without any complicated control or sensing modules has been developed as a long-term implantable artificial heart. Centrifugal pumps with impellers levitated by original hydrodynamic bearings were designed and have been modified through numerical analyses and in vi...
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| Veröffentlicht in: | Journal of artificial organs 2007-06, Vol.10 (2), p.71-76 |
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| container_title | Journal of artificial organs |
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| creator | Yamane, Takashi Maruyama, Osamu Nishida, Masahiro Kosaka, Ryo Sugiyama, Daisuke Miyamoto, Yusuke Kawamura, Hiroshi Kato, Takahisa Sano, Takeshi Okubo, Takeshi Sankai, Yoshiyuki Shigeta, Osamu Tsutsui, Tatsuo |
| description | A noncontact type centrifugal pump without any complicated control or sensing modules has been developed as a long-term implantable artificial heart. Centrifugal pumps with impellers levitated by original hydrodynamic bearings were designed and have been modified through numerical analyses and in vitro tests. The hemolysis level was reduced by changing the pressure distribution around the impeller and subsequently expanding the bearing gap. Thrombus formation in the bearing was examined with in vitro thrombogenesis tests and was reduced by changing the groove shapes to increase the bearing-gap flow to 3% of the external flow. Unnecessary vortices around the vanes were also eliminated by changing the number of vanes from four to six. |
| doi_str_mv | 10.1007/s10047-006-0370-z |
| format | Article |
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Centrifugal pumps with impellers levitated by original hydrodynamic bearings were designed and have been modified through numerical analyses and in vitro tests. The hemolysis level was reduced by changing the pressure distribution around the impeller and subsequently expanding the bearing gap. Thrombus formation in the bearing was examined with in vitro thrombogenesis tests and was reduced by changing the groove shapes to increase the bearing-gap flow to 3% of the external flow. Unnecessary vortices around the vanes were also eliminated by changing the number of vanes from four to six.</description><identifier>ISSN: 1434-7229</identifier><identifier>EISSN: 1619-0904</identifier><identifier>DOI: 10.1007/s10047-006-0370-z</identifier><identifier>PMID: 17574508</identifier><language>eng</language><publisher>Japan: Springer Nature B.V</publisher><subject>Animals ; Blood clots ; Heart, Artificial ; Hemolysis - physiology ; Hemorheology - instrumentation ; Materials Testing ; Pressure distribution ; Prosthesis Design ; Pumps ; Sheep ; Thrombosis - physiopathology</subject><ispartof>Journal of artificial organs, 2007-06, Vol.10 (2), p.71-76</ispartof><rights>The Japanese Society for Artificial Organs 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c449t-8ce821cea602eaf8111bf0114d6d3fc210f7b5282aec311b8de8a864100b59493</citedby><cites>FETCH-LOGICAL-c449t-8ce821cea602eaf8111bf0114d6d3fc210f7b5282aec311b8de8a864100b59493</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17574508$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yamane, Takashi</creatorcontrib><creatorcontrib>Maruyama, Osamu</creatorcontrib><creatorcontrib>Nishida, Masahiro</creatorcontrib><creatorcontrib>Kosaka, Ryo</creatorcontrib><creatorcontrib>Sugiyama, Daisuke</creatorcontrib><creatorcontrib>Miyamoto, Yusuke</creatorcontrib><creatorcontrib>Kawamura, Hiroshi</creatorcontrib><creatorcontrib>Kato, Takahisa</creatorcontrib><creatorcontrib>Sano, Takeshi</creatorcontrib><creatorcontrib>Okubo, Takeshi</creatorcontrib><creatorcontrib>Sankai, Yoshiyuki</creatorcontrib><creatorcontrib>Shigeta, Osamu</creatorcontrib><creatorcontrib>Tsutsui, Tatsuo</creatorcontrib><title>Hemocompatibility of a hydrodynamic levitation centrifugal blood pump</title><title>Journal of artificial organs</title><addtitle>J Artif Organs</addtitle><description>A noncontact type centrifugal pump without any complicated control or sensing modules has been developed as a long-term implantable artificial heart. 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Unnecessary vortices around the vanes were also eliminated by changing the number of vanes from four to six.</description><subject>Animals</subject><subject>Blood clots</subject><subject>Heart, Artificial</subject><subject>Hemolysis - physiology</subject><subject>Hemorheology - instrumentation</subject><subject>Materials Testing</subject><subject>Pressure distribution</subject><subject>Prosthesis Design</subject><subject>Pumps</subject><subject>Sheep</subject><subject>Thrombosis - physiopathology</subject><issn>1434-7229</issn><issn>1619-0904</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU1LxDAQhoMo7rr6A7xIQdBTdSZJ0-Yoy_oBC170HNI01S5tU5tW6P56s-yC4MHLzMA8M8w7LyGXCHcIkN77EHkaA4gYWArx9ojMUaCMQQI_DjVnPE4plTNy5v0GANMkhVMy22WeQDYnq2fbOOOaTg9VXtXVMEWujHT0ORW9K6ZWN5WJavtdDQFwbWRsO_RVOX7oOspr54qoG5vunJyUuvb24pAX5P1x9bZ8jtevTy_Lh3VsOJdDnBmbUTRWC6BWlxki5iUg8kIUrDQUoUzzhGZUW8NCLytspjPBg8w8kVyyBbnd7-169zVaP6im8sbWtW6tG72SCCIRQmAgb_4lUxBUUEwCeP0H3Lixb4MKFc5jHCSTOwr3lOmd970tVddXje4nhaB2Xqi9Fyp4oXZeqG2YuTpsHvPGFr8Th-ezHxKkhB0</recordid><startdate>200706</startdate><enddate>200706</enddate><creator>Yamane, Takashi</creator><creator>Maruyama, Osamu</creator><creator>Nishida, Masahiro</creator><creator>Kosaka, Ryo</creator><creator>Sugiyama, Daisuke</creator><creator>Miyamoto, Yusuke</creator><creator>Kawamura, Hiroshi</creator><creator>Kato, Takahisa</creator><creator>Sano, Takeshi</creator><creator>Okubo, Takeshi</creator><creator>Sankai, Yoshiyuki</creator><creator>Shigeta, Osamu</creator><creator>Tsutsui, Tatsuo</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200706</creationdate><title>Hemocompatibility of a hydrodynamic levitation centrifugal blood pump</title><author>Yamane, Takashi ; Maruyama, Osamu ; Nishida, Masahiro ; Kosaka, Ryo ; Sugiyama, Daisuke ; Miyamoto, Yusuke ; Kawamura, Hiroshi ; Kato, Takahisa ; Sano, Takeshi ; Okubo, Takeshi ; Sankai, Yoshiyuki ; Shigeta, Osamu ; Tsutsui, Tatsuo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c449t-8ce821cea602eaf8111bf0114d6d3fc210f7b5282aec311b8de8a864100b59493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Animals</topic><topic>Blood clots</topic><topic>Heart, Artificial</topic><topic>Hemolysis - 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Academic</collection><jtitle>Journal of artificial organs</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yamane, Takashi</au><au>Maruyama, Osamu</au><au>Nishida, Masahiro</au><au>Kosaka, Ryo</au><au>Sugiyama, Daisuke</au><au>Miyamoto, Yusuke</au><au>Kawamura, Hiroshi</au><au>Kato, Takahisa</au><au>Sano, Takeshi</au><au>Okubo, Takeshi</au><au>Sankai, Yoshiyuki</au><au>Shigeta, Osamu</au><au>Tsutsui, Tatsuo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hemocompatibility of a hydrodynamic levitation centrifugal blood pump</atitle><jtitle>Journal of artificial organs</jtitle><addtitle>J Artif Organs</addtitle><date>2007-06</date><risdate>2007</risdate><volume>10</volume><issue>2</issue><spage>71</spage><epage>76</epage><pages>71-76</pages><issn>1434-7229</issn><eissn>1619-0904</eissn><abstract>A noncontact type centrifugal pump without any complicated control or sensing modules has been developed as a long-term implantable artificial heart. Centrifugal pumps with impellers levitated by original hydrodynamic bearings were designed and have been modified through numerical analyses and in vitro tests. The hemolysis level was reduced by changing the pressure distribution around the impeller and subsequently expanding the bearing gap. Thrombus formation in the bearing was examined with in vitro thrombogenesis tests and was reduced by changing the groove shapes to increase the bearing-gap flow to 3% of the external flow. Unnecessary vortices around the vanes were also eliminated by changing the number of vanes from four to six.</abstract><cop>Japan</cop><pub>Springer Nature B.V</pub><pmid>17574508</pmid><doi>10.1007/s10047-006-0370-z</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1434-7229 |
| ispartof | Journal of artificial organs, 2007-06, Vol.10 (2), p.71-76 |
| issn | 1434-7229 1619-0904 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_910656661 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Animals Blood clots Heart, Artificial Hemolysis - physiology Hemorheology - instrumentation Materials Testing Pressure distribution Prosthesis Design Pumps Sheep Thrombosis - physiopathology |
| title | Hemocompatibility of a hydrodynamic levitation centrifugal blood pump |
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