Silymarin protects neurons from oxidative stress associated damages in focal cerebral ischemia: A behavioral, biochemical and immunohistological study in Wistar rats

Abstract Cerebral stroke is the third largest cause of death and the severe leading cause of disability, thus have astronomical financial and social burden worldwide. Accumulated evidence suggests that ROS can be scavenged through utilizing natural antioxidant compounds present in foods and medicina...

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Veröffentlicht in:	Journal of the neurological sciences 2011-10, Vol.309 (1), p.45-54
Hauptverfasser:	Raza, Syed Shadab, Khan, Mohd. Moshahid, Ashafaq, Mohammad, Ahmad, Ajmal, Khuwaja, Gulrana, Khan, Andleeb, Siddiqui, Mohammad Saeed, Safhi, Mohammed M, Islam, Fakhrul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism Apoptosis - drug effects Apoptosis - immunology Biological and medical sciences Brain Ischemia - immunology Brain Ischemia - pathology Brain Ischemia - prevention & control Immunohistochemistry Male Medical sciences Middle cerebral artery occlusion Motor Activity - drug effects Motor Activity - immunology Neurobehavioral Neurology Neurons - immunology Neurons - metabolism Neurons - pathology Neuroprotection Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Oxidative stress Oxidative Stress - drug effects Oxidative Stress - immunology Plant Extracts - pharmacology Plant Extracts - therapeutic use Rats Rats, Wistar Silybum marianum Silymarin Silymarin - pharmacology Silymarin - therapeutic use Vascular diseases and vascular malformations of the nervous system
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