A multiplexed electrospray process for single-step synthesis of stabilized polymer particles for drug delivery

While conventional methods for biodegradable particle production rely predominately on batch, emulsion preparation methods, an alternative process based on multiplexed electrospray (ES) can offer distinct advantages. These include enhanced encapsulation efficiency of hydrophilic and hydrophobic agen...

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Veröffentlicht in:	Journal of controlled release 2011-09, Vol.154 (2), p.203-210
Hauptverfasser:	Almería, Begoña, Fahmy, Tarek M., Gomez, Alessandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatible Materials - administration & dosage biodegradability Biological and medical sciences Chemistry, Pharmaceutical - methods Controlled drug delivery Doxorubicin Drug Delivery Systems - methods Drug Stability Electrospray emulsifiers emulsions encapsulation General pharmacology hydrophilicity Hydrophobic and Hydrophilic Interactions hydrophobicity Lactic Acid - administration & dosage Medical sciences Multiplexing nozzles Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments PLGA Polyglycolic Acid - administration & dosage polymers Reproducibility of Results Rhodamines - administration & dosage Surface modification
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