Benefits of adding fluticasone propionate/salmeterol to tiotropium in moderate to severe COPD

Summary Background Combining maintenance medications with different mechanisms of action may improve outcomes in COPD. In this study we evaluated the efficacy and safety of fluticasone/salmeterol (FSC) (250/50 mcg twice daily) when added to tiotropium (18 mcg once daily) (TIO) in subjects with sympt...

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Veröffentlicht in:	Respiratory medicine 2012-01, Vol.106 (1), p.91-101
Hauptverfasser:	Hanania, Nicola A, Crater, Glenn D, Morris, Andrea N, Emmett, Amanda H, O’Dell, Dianne M, Niewoehner, Dennis E
Format:	Artikel
Sprache:	eng
Schlagworte:	Albuterol - analogs & derivatives Albuterol - therapeutic use Androstadienes - therapeutic use Anxiety Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Bronchodilator Bronchodilator Agents - therapeutic use Chronic obstructive pulmonary disease, asthma COPD Double-Blind Method Drug Combinations Drug dosages Drug therapy Drug Therapy, Combination Female Fluticasone-Salmeterol Drug Combination Forced Expiratory Volume - drug effects Health Status Humans Inhaled corticosteroid Long-acting beta2-agonist Male Medical sciences Middle Aged Mortality Pharmacology. Drug treatments Pneumology Pulmonary Disease, Chronic Obstructive - drug therapy Pulmonary Disease, Chronic Obstructive - epidemiology Pulmonary Disease, Chronic Obstructive - physiopathology Pulmonary/Respiratory Quality of life Respiratory Function Tests Scopolamine Derivatives - therapeutic use Tiotropium Bromide Treatment Outcome Triple therapy United States - epidemiology
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