Tagging SNPs in REN, AGTR1 and AGTR2 genes and response of renin activity, angiotensin II and aldosterone concentrations to antihypertensive treatment in Kazakans

Hypothesis: Polymorphisms of REN, AGTR1 and AGTR2 may be associated with responses of renin–angiotensin–aldosterone system (RAAS) activity phenotypes to angiotensin-converting enzyme inhibitor (ACEI) antihypertensive treatment. Materials and methods: A total of 400 first diagnosed Kazak hypertensive...

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Veröffentlicht in:	Journal of the renin-angiotensin-aldosterone system 2011-12, Vol.12 (4), p.581-587
Hauptverfasser:	Yan, Weili, Zhang, Yuanming, Shan, Zimei, Wang, Qian, Huang, Yongdi, Wang, Chenchen, Yan, Kai
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone - blood Angiotensin II - blood Angiotensin-Converting Enzyme Inhibitors Antihypertensive Agents - therapeutic use Atenolol - therapeutic use Blood Pressure Captopril - therapeutic use China Double-Blind Method Ethnic Groups - genetics Female Genetic Association Studies Humans Hypertension - blood Hypertension - drug therapy Hypertension - genetics Male Middle Aged Polymorphism, Single Nucleotide - genetics Receptor, Angiotensin, Type 1 - genetics Receptor, Angiotensin, Type 2 - genetics Renin - blood Renin - genetics
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