Synthesis of Dragmacidin D via Direct C–H Couplings

Dragmacidin D, an emerging biologically active marine natural product, has attracted attention as a lead compound for treating Parkinson’s and Alzheimer’s diseases. Prominent structural features of this compound are the two indole–pyrazinone bonds and the presence of a polar aminoimidazole unit. We...

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Veröffentlicht in:	Journal of the American Chemical Society 2011-12, Vol.133 (49), p.19660-19663
Hauptverfasser:	Mandal, Debashis, Yamaguchi, Atsushi D, Yamaguchi, Junichiro, Itami, Kenichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Products - chemical synthesis Biological Products - chemistry Catalysis Indole Alkaloids Indoles - chemical synthesis Indoles - chemistry Models, Molecular Palladium - chemistry Piperazines - chemical synthesis Piperazines - chemistry Pyrazines - chemistry Thiophenes - chemistry
Online-Zugang:	Volltext
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