Clinical implications of acellular mucin pools in resected rectal cancer with pathological complete response to neoadjuvant chemoradiation

Approximately 20% of rectal cancers treated with neoadjuvant chemoradiation achieve a pathological complete response (pCR), which is associated with an improved oncological outcome. However, in a proportion of patients with a pCR, acellular pools of mucin are present in the surgical specimen. The ai...

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Veröffentlicht in:	Colorectal disease 2012-01, Vol.14 (1), p.62-67
Hauptverfasser:	de Campos-Lobato, L. F., Dietz, D. W., Stocchi, L., Vogel, J. D., Lavery, I. C., Goldblum, J. R., Skacel, M., Pelley, R. J., Kalady, M. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - chemistry Adenocarcinoma - pathology Adenocarcinoma - therapy Aged Chemoradiotherapy, Adjuvant chemotherapy Combined Modality Therapy Female Humans Male Middle Aged mucin Mucins - analysis Neoadjuvant Therapy neoadjuvant treatment Neoplasm Staging prognosis Prospective Studies radiotherapy Rectal cancer Rectal Neoplasms - chemistry Rectal Neoplasms - pathology Rectal Neoplasms - therapy surgery tumour response
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