Contributions of the ventromedial prefrontal cortex to goal-directed action selection

In this article, it will be argued that one of the key contributions of the ventromedial prefrontal cortex (vmPFC) to goal‐directed action selection lies both in retrieving the value of goals that are the putative outcomes of the decision process and in establishing a relative preference ranking for...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Annals of the New York Academy of Sciences 2011-12, Vol.1239 (1), p.118-129
1. Verfasser: O'Doherty, John P.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 129
container_issue 1
container_start_page 118
container_title Annals of the New York Academy of Sciences
container_volume 1239
creator O'Doherty, John P.
description In this article, it will be argued that one of the key contributions of the ventromedial prefrontal cortex (vmPFC) to goal‐directed action selection lies both in retrieving the value of goals that are the putative outcomes of the decision process and in establishing a relative preference ranking for these goals by taking into account the value of each of the different goals under consideration in a given decision‐making scenario. These goal‐value signals are then suggested to be used as an input into the on‐line computation of action values mediated by brain regions outside of the vmPFC, such as parts of the parietal cortex, supplementary motor cortex, and dorsal striatum. Collectively, these areas can be considered to be constituent elements of a multistage decision process whereby the values of different goals must first be represented and ranked before the value of different courses of action available for the pursuit of those goals can be computed.
doi_str_mv 10.1111/j.1749-6632.2011.06290.x
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_909751407</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>909751407</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5840-4317a9dc6eae7d360aace07d798be0213ebaae0aa3654b5586522a9551d388ab3</originalsourceid><addsrcrecordid>eNqNkU1v1DAQhi0EotvCX0CWOMAlYWzHXxekagsFqSorQVXBxXKSWciSXW_thG7_PU637IEDwhePxs88lv0SQhmULK83q5LpyhZKCV5yYKwExS2Uu0dkdjh4TGYAWhfGcnFEjlNaATBuKv2UHHHOKmkMm5GredgMsavHoQubRMOSDj-Q_sLcDGtsO9_TbcRlzFQumxAH3NEh0O_B90XbRWwGbKlvpnGasMf76hl5svR9wucP-wm5ev_uy_xDcfHp_OP89KJopKmgqATT3raNQo-6FQq8bxB0q62pETgTWHuPuSuUrGopjZKceysla4UxvhYn5NXeu43hZsQ0uHWXGux7v8EwJmfBaskq0Jl8_U-SAQOjhalsRl_-ha7CGDf5HY5ppbNQMMiU2VNNDCnlL3Lb2K19vMsqN4XkVm7Kwk1ZuCkkdx-S2-XRFw8XjHX-48Pgn1Qy8HYP3HY93v232F1-Pf08lVlQ7AVdynkdBD7-dEoLLd315bk7uz5bLBb8m7PiN8J7r5U</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1767751310</pqid></control><display><type>article</type><title>Contributions of the ventromedial prefrontal cortex to goal-directed action selection</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>O'Doherty, John P.</creator><creatorcontrib>O'Doherty, John P.</creatorcontrib><description>In this article, it will be argued that one of the key contributions of the ventromedial prefrontal cortex (vmPFC) to goal‐directed action selection lies both in retrieving the value of goals that are the putative outcomes of the decision process and in establishing a relative preference ranking for these goals by taking into account the value of each of the different goals under consideration in a given decision‐making scenario. These goal‐value signals are then suggested to be used as an input into the on‐line computation of action values mediated by brain regions outside of the vmPFC, such as parts of the parietal cortex, supplementary motor cortex, and dorsal striatum. Collectively, these areas can be considered to be constituent elements of a multistage decision process whereby the values of different goals must first be represented and ranked before the value of different courses of action available for the pursuit of those goals can be computed.</description><identifier>ISSN: 0077-8923</identifier><identifier>EISSN: 1749-6632</identifier><identifier>DOI: 10.1111/j.1749-6632.2011.06290.x</identifier><identifier>PMID: 22145881</identifier><identifier>CODEN: ANYAA9</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Animals ; Behavior, Animal ; Brain Mapping ; Corpus Striatum - physiology ; Decision Making ; Frontal Lobe - physiology ; Goals ; human ; Humans ; Models, Psychological ; Motor Cortex - physiology ; Neurons - physiology ; NMR ; Nuclear magnetic resonance ; Parietal Lobe - physiology ; Physiology, Comparative - methods ; Reward ; Social Behavior ; Social Values</subject><ispartof>Annals of the New York Academy of Sciences, 2011-12, Vol.1239 (1), p.118-129</ispartof><rights>2011 New York Academy of Sciences.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5840-4317a9dc6eae7d360aace07d798be0213ebaae0aa3654b5586522a9551d388ab3</citedby><cites>FETCH-LOGICAL-c5840-4317a9dc6eae7d360aace07d798be0213ebaae0aa3654b5586522a9551d388ab3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1749-6632.2011.06290.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1749-6632.2011.06290.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22145881$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>O'Doherty, John P.</creatorcontrib><title>Contributions of the ventromedial prefrontal cortex to goal-directed action selection</title><title>Annals of the New York Academy of Sciences</title><addtitle>Ann N Y Acad Sci</addtitle><description>In this article, it will be argued that one of the key contributions of the ventromedial prefrontal cortex (vmPFC) to goal‐directed action selection lies both in retrieving the value of goals that are the putative outcomes of the decision process and in establishing a relative preference ranking for these goals by taking into account the value of each of the different goals under consideration in a given decision‐making scenario. These goal‐value signals are then suggested to be used as an input into the on‐line computation of action values mediated by brain regions outside of the vmPFC, such as parts of the parietal cortex, supplementary motor cortex, and dorsal striatum. Collectively, these areas can be considered to be constituent elements of a multistage decision process whereby the values of different goals must first be represented and ranked before the value of different courses of action available for the pursuit of those goals can be computed.</description><subject>Animals</subject><subject>Behavior, Animal</subject><subject>Brain Mapping</subject><subject>Corpus Striatum - physiology</subject><subject>Decision Making</subject><subject>Frontal Lobe - physiology</subject><subject>Goals</subject><subject>human</subject><subject>Humans</subject><subject>Models, Psychological</subject><subject>Motor Cortex - physiology</subject><subject>Neurons - physiology</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Parietal Lobe - physiology</subject><subject>Physiology, Comparative - methods</subject><subject>Reward</subject><subject>Social Behavior</subject><subject>Social Values</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1v1DAQhi0EotvCX0CWOMAlYWzHXxekagsFqSorQVXBxXKSWciSXW_thG7_PU637IEDwhePxs88lv0SQhmULK83q5LpyhZKCV5yYKwExS2Uu0dkdjh4TGYAWhfGcnFEjlNaATBuKv2UHHHOKmkMm5GredgMsavHoQubRMOSDj-Q_sLcDGtsO9_TbcRlzFQumxAH3NEh0O_B90XbRWwGbKlvpnGasMf76hl5svR9wucP-wm5ev_uy_xDcfHp_OP89KJopKmgqATT3raNQo-6FQq8bxB0q62pETgTWHuPuSuUrGopjZKceysla4UxvhYn5NXeu43hZsQ0uHWXGux7v8EwJmfBaskq0Jl8_U-SAQOjhalsRl_-ha7CGDf5HY5ppbNQMMiU2VNNDCnlL3Lb2K19vMsqN4XkVm7Kwk1ZuCkkdx-S2-XRFw8XjHX-48Pgn1Qy8HYP3HY93v232F1-Pf08lVlQ7AVdynkdBD7-dEoLLd315bk7uz5bLBb8m7PiN8J7r5U</recordid><startdate>201112</startdate><enddate>201112</enddate><creator>O'Doherty, John P.</creator><general>Blackwell Publishing Inc</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7ST</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>SOI</scope><scope>7X8</scope></search><sort><creationdate>201112</creationdate><title>Contributions of the ventromedial prefrontal cortex to goal-directed action selection</title><author>O'Doherty, John P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5840-4317a9dc6eae7d360aace07d798be0213ebaae0aa3654b5586522a9551d388ab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Animals</topic><topic>Behavior, Animal</topic><topic>Brain Mapping</topic><topic>Corpus Striatum - physiology</topic><topic>Decision Making</topic><topic>Frontal Lobe - physiology</topic><topic>Goals</topic><topic>human</topic><topic>Humans</topic><topic>Models, Psychological</topic><topic>Motor Cortex - physiology</topic><topic>Neurons - physiology</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Parietal Lobe - physiology</topic><topic>Physiology, Comparative - methods</topic><topic>Reward</topic><topic>Social Behavior</topic><topic>Social Values</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>O'Doherty, John P.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Environment Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>Environment Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the New York Academy of Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>O'Doherty, John P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Contributions of the ventromedial prefrontal cortex to goal-directed action selection</atitle><jtitle>Annals of the New York Academy of Sciences</jtitle><addtitle>Ann N Y Acad Sci</addtitle><date>2011-12</date><risdate>2011</risdate><volume>1239</volume><issue>1</issue><spage>118</spage><epage>129</epage><pages>118-129</pages><issn>0077-8923</issn><eissn>1749-6632</eissn><coden>ANYAA9</coden><abstract>In this article, it will be argued that one of the key contributions of the ventromedial prefrontal cortex (vmPFC) to goal‐directed action selection lies both in retrieving the value of goals that are the putative outcomes of the decision process and in establishing a relative preference ranking for these goals by taking into account the value of each of the different goals under consideration in a given decision‐making scenario. These goal‐value signals are then suggested to be used as an input into the on‐line computation of action values mediated by brain regions outside of the vmPFC, such as parts of the parietal cortex, supplementary motor cortex, and dorsal striatum. Collectively, these areas can be considered to be constituent elements of a multistage decision process whereby the values of different goals must first be represented and ranked before the value of different courses of action available for the pursuit of those goals can be computed.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>22145881</pmid><doi>10.1111/j.1749-6632.2011.06290.x</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0077-8923
ispartof Annals of the New York Academy of Sciences, 2011-12, Vol.1239 (1), p.118-129
issn 0077-8923
1749-6632
language eng
recordid cdi_proquest_miscellaneous_909751407
source MEDLINE; Wiley Online Library All Journals
subjects Animals
Behavior, Animal
Brain Mapping
Corpus Striatum - physiology
Decision Making
Frontal Lobe - physiology
Goals
human
Humans
Models, Psychological
Motor Cortex - physiology
Neurons - physiology
NMR
Nuclear magnetic resonance
Parietal Lobe - physiology
Physiology, Comparative - methods
Reward
Social Behavior
Social Values
title Contributions of the ventromedial prefrontal cortex to goal-directed action selection
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T15%3A39%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Contributions%20of%20the%20ventromedial%20prefrontal%20cortex%20to%20goal-directed%20action%20selection&rft.jtitle=Annals%20of%20the%20New%20York%20Academy%20of%20Sciences&rft.au=O'Doherty,%20John%20P.&rft.date=2011-12&rft.volume=1239&rft.issue=1&rft.spage=118&rft.epage=129&rft.pages=118-129&rft.issn=0077-8923&rft.eissn=1749-6632&rft.coden=ANYAA9&rft_id=info:doi/10.1111/j.1749-6632.2011.06290.x&rft_dat=%3Cproquest_cross%3E909751407%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1767751310&rft_id=info:pmid/22145881&rfr_iscdi=true