A rapid and sensitive method for the analysis of brain monoamine neurotransmitters using ultra-fast liquid chromatography coupled to electrochemical detection

► Catecholamines and indolamines are the most studied monoamines in neuroscience. ► Time of routine analyses by conventional HPLC and electrochemical detection is too long. ► Use of sub-2 μm particles increases the throughput of analysis using ultra-fast HPLC. ► Brain monoamines can be determined in...

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Veröffentlicht in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2011-12, Vol.879 (32), p.3871-3878
Hauptverfasser:	Parrot, Sandrine, Neuzeret, Pierre-Charles, Denoroy, Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - analysis Analysis Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Brain Brain Chemistry Brain samples Catecholamines - analysis Cats Chromatography Chromatography, High Pressure Liquid - methods detection limit dopamine Drug Stability Electrochemical detection electrochemistry Fundamental and applied biological sciences. Psychology General pharmacology High performance liquid chromatography homovanillic acid Homovanillic Acid - analysis Limit of Detection Linearity Liquid chromatography Mathematical analysis Medical sciences Metabolite Metabolites Mice Monoamine monoamines Neurotransmitter Agents - analysis Neurotransmitters norepinephrine Pharmacology. Drug treatments Rats Reproducibility of Results reversed-phase high performance liquid chromatography serotonin Serotonin - analysis ultra-performance liquid chromatography Ultrafast high performance liquid chromatography ultrafast liquid chromatography
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