Complications, Adverse Events, and Additional Intraocular Surgery 1 Year After Cataract Surgery in the Infant Aphakia Treatment Study
Purpose To compare rates and severity of complications between infants undergoing cataract surgery with and without intraocular lens (IOL) implantation. Design Prospective, randomized clinical trial. Participants The Infant Aphakia Treatment Study (IATS) is a randomized, multicenter (n = 12) clinica...
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| Veröffentlicht in: | Ophthalmology (Rochester, Minn.) Minn.), 2011-12, Vol.118 (12), p.2330-2334 |
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| creator | Plager, David A., MD Lynn, Michael J., MS Buckley, Edward G., MD Wilson, M. Edward, MD Lambert, Scott R., MD |
| description | Purpose To compare rates and severity of complications between infants undergoing cataract surgery with and without intraocular lens (IOL) implantation. Design Prospective, randomized clinical trial. Participants The Infant Aphakia Treatment Study (IATS) is a randomized, multicenter (n = 12) clinical trial comparing treatment of aphakia with a primary IOL or contact lens in 114 infants with unilateral congenital cataract. Intervention Infants underwent cataract surgery with or without placement of an IOL. Main Outcome Measures The rate, character, and severity of intraoperative complications (ICs), adverse events (AEs), and additional intraocular surgeries (AISs) during the first postoperative year in the 2 groups were analyzed. Results There were more patients with ICs (28% vs. 11%; P = 0.031), AEs (77% vs. 25%; P |
| doi_str_mv | 10.1016/j.ophtha.2011.06.017 |
| format | Article |
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Edward, MD ; Lambert, Scott R., MD</creator><creatorcontrib>Plager, David A., MD ; Lynn, Michael J., MS ; Buckley, Edward G., MD ; Wilson, M. Edward, MD ; Lambert, Scott R., MD ; Infant Aphakia Treatment Study Group</creatorcontrib><description>Purpose To compare rates and severity of complications between infants undergoing cataract surgery with and without intraocular lens (IOL) implantation. Design Prospective, randomized clinical trial. Participants The Infant Aphakia Treatment Study (IATS) is a randomized, multicenter (n = 12) clinical trial comparing treatment of aphakia with a primary IOL or contact lens in 114 infants with unilateral congenital cataract. Intervention Infants underwent cataract surgery with or without placement of an IOL. Main Outcome Measures The rate, character, and severity of intraoperative complications (ICs), adverse events (AEs), and additional intraocular surgeries (AISs) during the first postoperative year in the 2 groups were analyzed. Results There were more patients with ICs (28% vs. 11%; P = 0.031), AEs (77% vs. 25%; P <0.0001), and AISs (63% vs. 12%; P <0.0001) in the IOL group than the contact lens group. Iris prolapse was the most common IC. The most common AE was visual axis opacification, and the most common additional intraocular reoperation was a clearing of visual axis opacification. Conclusions The rates of ICs, AEs, and AISs 1 year after surgery were numerically higher in the IOL group, but their functional impact does not clearly favor either treatment group. Financial Disclosure(s) The author(s) have no proprietary or commercial interest in any materials discussed in this article.</description><identifier>ISSN: 0161-6420</identifier><identifier>EISSN: 1549-4713</identifier><identifier>DOI: 10.1016/j.ophtha.2011.06.017</identifier><identifier>PMID: 21925737</identifier><identifier>CODEN: OPHTDG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aphakia, Postcataract - physiopathology ; Aphakia, Postcataract - therapy ; Biological and medical sciences ; Capsule Opacification - etiology ; Capsule Opacification - surgery ; Cataract - congenital ; Cataract Extraction ; Contact Lenses ; Humans ; Infant ; Infant, Newborn ; Intraoperative Complications ; Lens diseases ; Lens Implantation, Intraocular ; Medical sciences ; Miscellaneous ; Ophthalmology ; Postoperative Complications ; Prospective Studies ; Reoperation ; Visual Acuity - physiology</subject><ispartof>Ophthalmology (Rochester, Minn.), 2011-12, Vol.118 (12), p.2330-2334</ispartof><rights>American Academy of Ophthalmology</rights><rights>2011 American Academy of Ophthalmology</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c558t-d1cee8408d6806300e7f9882cd143674adc07f6a1576a9c610e41404c5cdd6d63</citedby><cites>FETCH-LOGICAL-c558t-d1cee8408d6806300e7f9882cd143674adc07f6a1576a9c610e41404c5cdd6d63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ophtha.2011.06.017$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25286144$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21925737$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Plager, David A., MD</creatorcontrib><creatorcontrib>Lynn, Michael J., MS</creatorcontrib><creatorcontrib>Buckley, Edward G., MD</creatorcontrib><creatorcontrib>Wilson, M. Edward, MD</creatorcontrib><creatorcontrib>Lambert, Scott R., MD</creatorcontrib><creatorcontrib>Infant Aphakia Treatment Study Group</creatorcontrib><title>Complications, Adverse Events, and Additional Intraocular Surgery 1 Year After Cataract Surgery in the Infant Aphakia Treatment Study</title><title>Ophthalmology (Rochester, Minn.)</title><addtitle>Ophthalmology</addtitle><description>Purpose To compare rates and severity of complications between infants undergoing cataract surgery with and without intraocular lens (IOL) implantation. Design Prospective, randomized clinical trial. Participants The Infant Aphakia Treatment Study (IATS) is a randomized, multicenter (n = 12) clinical trial comparing treatment of aphakia with a primary IOL or contact lens in 114 infants with unilateral congenital cataract. Intervention Infants underwent cataract surgery with or without placement of an IOL. Main Outcome Measures The rate, character, and severity of intraoperative complications (ICs), adverse events (AEs), and additional intraocular surgeries (AISs) during the first postoperative year in the 2 groups were analyzed. Results There were more patients with ICs (28% vs. 11%; P = 0.031), AEs (77% vs. 25%; P <0.0001), and AISs (63% vs. 12%; P <0.0001) in the IOL group than the contact lens group. Iris prolapse was the most common IC. The most common AE was visual axis opacification, and the most common additional intraocular reoperation was a clearing of visual axis opacification. Conclusions The rates of ICs, AEs, and AISs 1 year after surgery were numerically higher in the IOL group, but their functional impact does not clearly favor either treatment group. Financial Disclosure(s) The author(s) have no proprietary or commercial interest in any materials discussed in this article.</description><subject>Aphakia, Postcataract - physiopathology</subject><subject>Aphakia, Postcataract - therapy</subject><subject>Biological and medical sciences</subject><subject>Capsule Opacification - etiology</subject><subject>Capsule Opacification - surgery</subject><subject>Cataract - congenital</subject><subject>Cataract Extraction</subject><subject>Contact Lenses</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Intraoperative Complications</subject><subject>Lens diseases</subject><subject>Lens Implantation, Intraocular</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Ophthalmology</subject><subject>Postoperative Complications</subject><subject>Prospective Studies</subject><subject>Reoperation</subject><subject>Visual Acuity - physiology</subject><issn>0161-6420</issn><issn>1549-4713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFksGO0zAQhiMEYsvCGyDkC9oLLTOJ4yQXpKpa2JVW4tDlwMka7Al1N02K7VTqA_DeOGrZlbhwssbz_TOjfybL3iIsEFB93C6G_SZuaJED4gLUArB6ls2wlM1cVlg8z2YJw7mSOVxkr0LYAoBShXyZXeTY5GVVVLPs92rY7TtnKLqhDx_E0h7YBxbXB-5jiqm36c-6KU2duO2jp8GMHXmxHv1P9keB4juncNlG9mJFkTyZ-Jh1vYgbTsKW-iiW-w09OBL3ninuUguxjqM9vs5etNQFfnN-L7Nvn6_vVzfzu69fblfLu7kpyzrOLRrmWkJtVQ2qAOCqbeo6NxZloSpJ1kDVKsKyUtQYhcASJUhTGmuVVcVldnWqu_fDr5FD1DsXDHcd9TyMQTdQV7KQdZNIeSKNH0Lw3Oq9dzvyR42gJ__1Vp_815P_GpRO_ifZu3OD8ceO7aPor-EJeH8GKBjqWk-9ceGJK_NaoZSJ-3TiONlxcOx1MI57w9Z5NlHbwf1vkn8LmM71adHdAx85bIfRp4UGjTrkGvR6upXpVBABSgWy-ANl8Lqr</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Plager, David A., MD</creator><creator>Lynn, Michael J., MS</creator><creator>Buckley, Edward G., MD</creator><creator>Wilson, M. Edward, MD</creator><creator>Lambert, Scott R., MD</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>Complications, Adverse Events, and Additional Intraocular Surgery 1 Year After Cataract Surgery in the Infant Aphakia Treatment Study</title><author>Plager, David A., MD ; Lynn, Michael J., MS ; Buckley, Edward G., MD ; Wilson, M. Edward, MD ; Lambert, Scott R., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c558t-d1cee8408d6806300e7f9882cd143674adc07f6a1576a9c610e41404c5cdd6d63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aphakia, Postcataract - physiopathology</topic><topic>Aphakia, Postcataract - therapy</topic><topic>Biological and medical sciences</topic><topic>Capsule Opacification - etiology</topic><topic>Capsule Opacification - surgery</topic><topic>Cataract - congenital</topic><topic>Cataract Extraction</topic><topic>Contact Lenses</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Intraoperative Complications</topic><topic>Lens diseases</topic><topic>Lens Implantation, Intraocular</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Ophthalmology</topic><topic>Postoperative Complications</topic><topic>Prospective Studies</topic><topic>Reoperation</topic><topic>Visual Acuity - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Plager, David A., MD</creatorcontrib><creatorcontrib>Lynn, Michael J., MS</creatorcontrib><creatorcontrib>Buckley, Edward G., MD</creatorcontrib><creatorcontrib>Wilson, M. Edward, MD</creatorcontrib><creatorcontrib>Lambert, Scott R., MD</creatorcontrib><creatorcontrib>Infant Aphakia Treatment Study Group</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Ophthalmology (Rochester, Minn.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Plager, David A., MD</au><au>Lynn, Michael J., MS</au><au>Buckley, Edward G., MD</au><au>Wilson, M. Edward, MD</au><au>Lambert, Scott R., MD</au><aucorp>Infant Aphakia Treatment Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Complications, Adverse Events, and Additional Intraocular Surgery 1 Year After Cataract Surgery in the Infant Aphakia Treatment Study</atitle><jtitle>Ophthalmology (Rochester, Minn.)</jtitle><addtitle>Ophthalmology</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>118</volume><issue>12</issue><spage>2330</spage><epage>2334</epage><pages>2330-2334</pages><issn>0161-6420</issn><eissn>1549-4713</eissn><coden>OPHTDG</coden><abstract>Purpose To compare rates and severity of complications between infants undergoing cataract surgery with and without intraocular lens (IOL) implantation. Design Prospective, randomized clinical trial. Participants The Infant Aphakia Treatment Study (IATS) is a randomized, multicenter (n = 12) clinical trial comparing treatment of aphakia with a primary IOL or contact lens in 114 infants with unilateral congenital cataract. Intervention Infants underwent cataract surgery with or without placement of an IOL. Main Outcome Measures The rate, character, and severity of intraoperative complications (ICs), adverse events (AEs), and additional intraocular surgeries (AISs) during the first postoperative year in the 2 groups were analyzed. Results There were more patients with ICs (28% vs. 11%; P = 0.031), AEs (77% vs. 25%; P <0.0001), and AISs (63% vs. 12%; P <0.0001) in the IOL group than the contact lens group. Iris prolapse was the most common IC. The most common AE was visual axis opacification, and the most common additional intraocular reoperation was a clearing of visual axis opacification. Conclusions The rates of ICs, AEs, and AISs 1 year after surgery were numerically higher in the IOL group, but their functional impact does not clearly favor either treatment group. Financial Disclosure(s) The author(s) have no proprietary or commercial interest in any materials discussed in this article.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>21925737</pmid><doi>10.1016/j.ophtha.2011.06.017</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Aphakia, Postcataract - physiopathology Aphakia, Postcataract - therapy Biological and medical sciences Capsule Opacification - etiology Capsule Opacification - surgery Cataract - congenital Cataract Extraction Contact Lenses Humans Infant Infant, Newborn Intraoperative Complications Lens diseases Lens Implantation, Intraocular Medical sciences Miscellaneous Ophthalmology Postoperative Complications Prospective Studies Reoperation Visual Acuity - physiology |
| title | Complications, Adverse Events, and Additional Intraocular Surgery 1 Year After Cataract Surgery in the Infant Aphakia Treatment Study |
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