Dental sedation for patients with intellectual disability: a prospective study of manual control versus Bispectral Index-guided target-controlled infusion of propofol
Abstract Study Objective To investigate the use of propofol sedation using Bispectral Index (BIS)-guided target-controlled infusion (TCI) in dental patients with intellectual disability. Design Single-center, prospective, randomized clinical trial. Setting Academic outpatient clinic. Subjects 40 ASA...
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Veröffentlicht in: | Journal of clinical anesthesia 2011-12, Vol.23 (8), p.636-642 |
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creator | Sakaguchi, Mai, DDS Higuchi, Hitoshi, DDS, PhD Maeda, Shigeru, DDS, PhD Miyawaki, Takuya, DDS, PhD |
description | Abstract Study Objective To investigate the use of propofol sedation using Bispectral Index (BIS)-guided target-controlled infusion (TCI) in dental patients with intellectual disability. Design Single-center, prospective, randomized clinical trial. Setting Academic outpatient clinic. Subjects 40 ASA physical status 1 and 2 patients with intellectual disability. Interventions Patients were randomized to two groups. The manual control (MC) group (n = 20) had sedation by manually controlled infusion of propofol without a BIS index monitor. The BIS-TCI group (n = 20) had sedation by BIS-guided TCI of propofol. Measurements The required dose of propofol, recovery time for the eyelash reflex, and spontaneous eye opening times were recorded. Main Results BIS-TCI significantly reduced the dose of propofol and shortened the recovery times for eyelash reflex and spontaneous eye opening. Conclusion Propofol sedation using BIS-guided TCI is a useful and safe method in the management of patients with intellectual disability. |
doi_str_mv | 10.1016/j.jclinane.2011.04.008 |
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Design Single-center, prospective, randomized clinical trial. Setting Academic outpatient clinic. Subjects 40 ASA physical status 1 and 2 patients with intellectual disability. Interventions Patients were randomized to two groups. The manual control (MC) group (n = 20) had sedation by manually controlled infusion of propofol without a BIS index monitor. The BIS-TCI group (n = 20) had sedation by BIS-guided TCI of propofol. Measurements The required dose of propofol, recovery time for the eyelash reflex, and spontaneous eye opening times were recorded. Main Results BIS-TCI significantly reduced the dose of propofol and shortened the recovery times for eyelash reflex and spontaneous eye opening. Conclusion Propofol sedation using BIS-guided TCI is a useful and safe method in the management of patients with intellectual disability.</description><identifier>ISSN: 0952-8180</identifier><identifier>EISSN: 1873-4529</identifier><identifier>DOI: 10.1016/j.jclinane.2011.04.008</identifier><identifier>PMID: 22137516</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Airway management ; Ambulatory Care ; Anesthesia ; Anesthesia & Perioperative Care ; Anesthesia Recovery Period ; Anesthesia, Dental - methods ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anesthetics, Intravenous - administration & dosage ; Anesthetics, Intravenous - pharmacology ; Behavior ; Biological and medical sciences ; Bispectral index ; Consciousness Monitors ; Dental treatments ; Disability ; Dose-Response Relationship, Drug ; Female ; Hospitals ; Humans ; Infusions, Intravenous ; Intellectual Disability ; Intravenous sedation ; Male ; Medical sciences ; Mental retardation ; Pain Medicine ; Propofol - administration & dosage ; Propofol - pharmacology ; Prospective Studies ; Single-Blind Method ; Target-controlled infusion ; Time Factors ; Verbal communication ; Young Adult</subject><ispartof>Journal of clinical anesthesia, 2011-12, Vol.23 (8), p.636-642</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c528t-af3394f5eef4683f094575cc43f3d712f0409e654d8cbfec412019d41d360f6c3</citedby><cites>FETCH-LOGICAL-c528t-af3394f5eef4683f094575cc43f3d712f0409e654d8cbfec412019d41d360f6c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0952818011003230$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25305355$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22137516$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sakaguchi, Mai, DDS</creatorcontrib><creatorcontrib>Higuchi, Hitoshi, DDS, PhD</creatorcontrib><creatorcontrib>Maeda, Shigeru, DDS, PhD</creatorcontrib><creatorcontrib>Miyawaki, Takuya, DDS, PhD</creatorcontrib><title>Dental sedation for patients with intellectual disability: a prospective study of manual control versus Bispectral Index-guided target-controlled infusion of propofol</title><title>Journal of clinical anesthesia</title><addtitle>J Clin Anesth</addtitle><description>Abstract Study Objective To investigate the use of propofol sedation using Bispectral Index (BIS)-guided target-controlled infusion (TCI) in dental patients with intellectual disability. Design Single-center, prospective, randomized clinical trial. Setting Academic outpatient clinic. Subjects 40 ASA physical status 1 and 2 patients with intellectual disability. Interventions Patients were randomized to two groups. The manual control (MC) group (n = 20) had sedation by manually controlled infusion of propofol without a BIS index monitor. The BIS-TCI group (n = 20) had sedation by BIS-guided TCI of propofol. Measurements The required dose of propofol, recovery time for the eyelash reflex, and spontaneous eye opening times were recorded. Main Results BIS-TCI significantly reduced the dose of propofol and shortened the recovery times for eyelash reflex and spontaneous eye opening. Conclusion Propofol sedation using BIS-guided TCI is a useful and safe method in the management of patients with intellectual disability.</description><subject>Adult</subject><subject>Airway management</subject><subject>Ambulatory Care</subject><subject>Anesthesia</subject><subject>Anesthesia & Perioperative Care</subject><subject>Anesthesia Recovery Period</subject><subject>Anesthesia, Dental - methods</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anesthetics, Intravenous - administration & dosage</subject><subject>Anesthetics, Intravenous - pharmacology</subject><subject>Behavior</subject><subject>Biological and medical sciences</subject><subject>Bispectral index</subject><subject>Consciousness Monitors</subject><subject>Dental treatments</subject><subject>Disability</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>Intellectual Disability</subject><subject>Intravenous sedation</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental retardation</subject><subject>Pain Medicine</subject><subject>Propofol - administration & dosage</subject><subject>Propofol - pharmacology</subject><subject>Prospective Studies</subject><subject>Single-Blind Method</subject><subject>Target-controlled infusion</subject><subject>Time Factors</subject><subject>Verbal communication</subject><subject>Young Adult</subject><issn>0952-8180</issn><issn>1873-4529</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFks1u1DAQxyMEokvhFSpLCHFKGMd2NuGAgPJVqRIH4Gx57XHxkk22trOwL8RzMmG3VOqFg2Vr5jeffxfFGYeKA29erKu17cNgBqxq4LwCWQG094oFb5eilKru7hcL6FRdtryFk-JRSmsAIAd_WJzUNRdLxZtF8fsdDtn0LKEzOYwD82NkW3qSObGfIX9nYcjY92jzRJwLyaxCH_L-JTNsG8e0JU_YIUt5cns2erYxw0zacchx7NkOY5oSexv-kpE8F4PDX-XVFBw6lk28wlwe6Z4sYfBTmluhXFRgO_qxf1w88KZP-OR4nxbfPrz_ev6pvPz88eL8zWVpVd3m0nghOukVopdNKzx0Ui2VtVJ44Za89iChw0ZJ19qVRys5La9zkjvRgG-sOC2eH_JS4esJU9abkCyNT4sep6Q7aJeSt0IS-fQOuR6nOFBzmoMQNR2piGoOlKVNpYheb2PYmLgnSM9C6rW-EVLPQmqQmoSkwLNj-mm1Qfcv7EY5Ap4dAZOs6X00gw3pllMClFBzB68PHNLadgGjTpbEtehCJD20G8P_e3l1J8VMBar6A_eYbufWqdagv8zfbv51nAOIWoD4A5yx19c</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Sakaguchi, Mai, DDS</creator><creator>Higuchi, Hitoshi, DDS, PhD</creator><creator>Maeda, Shigeru, DDS, PhD</creator><creator>Miyawaki, Takuya, DDS, PhD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>Dental sedation for patients with intellectual disability: a prospective study of manual control versus Bispectral Index-guided target-controlled infusion of propofol</title><author>Sakaguchi, Mai, DDS ; Higuchi, Hitoshi, DDS, PhD ; Maeda, Shigeru, DDS, PhD ; Miyawaki, Takuya, DDS, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c528t-af3394f5eef4683f094575cc43f3d712f0409e654d8cbfec412019d41d360f6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Airway management</topic><topic>Ambulatory Care</topic><topic>Anesthesia</topic><topic>Anesthesia & Perioperative Care</topic><topic>Anesthesia Recovery Period</topic><topic>Anesthesia, Dental - methods</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anesthetics, Intravenous - administration & dosage</topic><topic>Anesthetics, Intravenous - pharmacology</topic><topic>Behavior</topic><topic>Biological and medical sciences</topic><topic>Bispectral index</topic><topic>Consciousness Monitors</topic><topic>Dental treatments</topic><topic>Disability</topic><topic>Dose-Response Relationship, Drug</topic><topic>Female</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infusions, Intravenous</topic><topic>Intellectual Disability</topic><topic>Intravenous sedation</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental retardation</topic><topic>Pain Medicine</topic><topic>Propofol - administration & dosage</topic><topic>Propofol - pharmacology</topic><topic>Prospective Studies</topic><topic>Single-Blind Method</topic><topic>Target-controlled infusion</topic><topic>Time Factors</topic><topic>Verbal communication</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sakaguchi, Mai, DDS</creatorcontrib><creatorcontrib>Higuchi, Hitoshi, DDS, PhD</creatorcontrib><creatorcontrib>Maeda, Shigeru, DDS, PhD</creatorcontrib><creatorcontrib>Miyawaki, Takuya, DDS, PhD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sakaguchi, Mai, DDS</au><au>Higuchi, Hitoshi, DDS, PhD</au><au>Maeda, Shigeru, DDS, PhD</au><au>Miyawaki, Takuya, DDS, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dental sedation for patients with intellectual disability: a prospective study of manual control versus Bispectral Index-guided target-controlled infusion of propofol</atitle><jtitle>Journal of clinical anesthesia</jtitle><addtitle>J Clin Anesth</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>23</volume><issue>8</issue><spage>636</spage><epage>642</epage><pages>636-642</pages><issn>0952-8180</issn><eissn>1873-4529</eissn><abstract>Abstract Study Objective To investigate the use of propofol sedation using Bispectral Index (BIS)-guided target-controlled infusion (TCI) in dental patients with intellectual disability. Design Single-center, prospective, randomized clinical trial. Setting Academic outpatient clinic. Subjects 40 ASA physical status 1 and 2 patients with intellectual disability. Interventions Patients were randomized to two groups. The manual control (MC) group (n = 20) had sedation by manually controlled infusion of propofol without a BIS index monitor. The BIS-TCI group (n = 20) had sedation by BIS-guided TCI of propofol. Measurements The required dose of propofol, recovery time for the eyelash reflex, and spontaneous eye opening times were recorded. Main Results BIS-TCI significantly reduced the dose of propofol and shortened the recovery times for eyelash reflex and spontaneous eye opening. Conclusion Propofol sedation using BIS-guided TCI is a useful and safe method in the management of patients with intellectual disability.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>22137516</pmid><doi>10.1016/j.jclinane.2011.04.008</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Airway management Ambulatory Care Anesthesia Anesthesia & Perioperative Care Anesthesia Recovery Period Anesthesia, Dental - methods Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Intravenous - administration & dosage Anesthetics, Intravenous - pharmacology Behavior Biological and medical sciences Bispectral index Consciousness Monitors Dental treatments Disability Dose-Response Relationship, Drug Female Hospitals Humans Infusions, Intravenous Intellectual Disability Intravenous sedation Male Medical sciences Mental retardation Pain Medicine Propofol - administration & dosage Propofol - pharmacology Prospective Studies Single-Blind Method Target-controlled infusion Time Factors Verbal communication Young Adult |
title | Dental sedation for patients with intellectual disability: a prospective study of manual control versus Bispectral Index-guided target-controlled infusion of propofol |
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