Walking and Thinking in Persons With Multiple Sclerosis Who Vary in Disability
Abstract Sosnoff JJ, Boes MK, Sandroff BM, Socie MJ, Pula JH, Motl RW. Walking and thinking in persons with multiple sclerosis who vary in disability. Objective To examine the effect of a cognitive task on spatiotemporal parameters of gait in persons with multiple sclerosis (MS) with varying disabil...
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| Veröffentlicht in: | Archives of physical medicine and rehabilitation 2011-12, Vol.92 (12), p.2028-2033 |
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| creator | Sosnoff, Jacob J., PhD Boes, Morgan K., BS Sandroff, Brian M., BS Socie, Michael J., BS Pula, John H., MD Motl, Robert W., PhD |
| description | Abstract Sosnoff JJ, Boes MK, Sandroff BM, Socie MJ, Pula JH, Motl RW. Walking and thinking in persons with multiple sclerosis who vary in disability. Objective To examine the effect of a cognitive task on spatiotemporal parameters of gait in persons with multiple sclerosis (MS) with varying disability. Design Cohort. Setting Testing occurred at a local hospital. Participants Community-living persons (N=78) with MS participated in this investigation. They were divided into 3 groups based on Expanded Disability Status Scale (EDSS) scores: mild (2.0–3.5 EDSS; n=21); moderate (4.0–5.5 EDSS; n=25); and severe (6.0–6.5 EDSS; n=32). Interventions Not applicable. Main Outcome Measures Participants walked at a self-selected pace on an electronic pathway, which recorded spatiotemporal parameters of gait, in 4 separate trials and completed a cognitive task in the last 2 trials. The effect of the cognitive task was quantified as the change in spatiotemporal parameters of gait. Results There was an overall decline in gait with the additive cognitive task. The magnitude of the adverse changes ranged from 1.8% for step length ( P =.02 ) to 12% for gait velocity ( P |
| doi_str_mv | 10.1016/j.apmr.2011.07.004 |
| format | Article |
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Walking and thinking in persons with multiple sclerosis who vary in disability. Objective To examine the effect of a cognitive task on spatiotemporal parameters of gait in persons with multiple sclerosis (MS) with varying disability. Design Cohort. Setting Testing occurred at a local hospital. Participants Community-living persons (N=78) with MS participated in this investigation. They were divided into 3 groups based on Expanded Disability Status Scale (EDSS) scores: mild (2.0–3.5 EDSS; n=21); moderate (4.0–5.5 EDSS; n=25); and severe (6.0–6.5 EDSS; n=32). Interventions Not applicable. Main Outcome Measures Participants walked at a self-selected pace on an electronic pathway, which recorded spatiotemporal parameters of gait, in 4 separate trials and completed a cognitive task in the last 2 trials. The effect of the cognitive task was quantified as the change in spatiotemporal parameters of gait. Results There was an overall decline in gait with the additive cognitive task. The magnitude of the adverse changes ranged from 1.8% for step length ( P =.02 ) to 12% for gait velocity ( P <.001 ) . Moreover, adverse changes in gait function were greatest in the severe and moderate disability group ( P <.05). Conclusions Persons with MS have impaired walking while doing a cognitive task, and the adverse effect of a cognitive task on walking function is greatest in persons with severe and moderate disability. Difficulty walking while thinking has implications for everyday life and may be related to the risk of falls. Further work is needed to determine whether the adverse effect of an additive cognitive task can be minimized with rehabilitative interventions.</description><identifier>ISSN: 0003-9993</identifier><identifier>EISSN: 1532-821X</identifier><identifier>DOI: 10.1016/j.apmr.2011.07.004</identifier><identifier>PMID: 22133253</identifier><identifier>CODEN: APMHAI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Cognition ; Cognitive Dysfunction - etiology ; Disabled Persons - psychology ; Disabled Persons - rehabilitation ; Diseases of the osteoarticular system ; Female ; Gait ; Humans ; Male ; Medical sciences ; Memory Disorders - etiology ; Middle Aged ; Miscellaneous ; Miscellaneous. Osteoarticular involvement in other diseases ; Multiple Sclerosis - complications ; Multiple Sclerosis - psychology ; Multiple Sclerosis - rehabilitation ; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis ; Neurology ; Physical Medicine and Rehabilitation ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Rehabilitation ; Self-Help Devices ; Task Performance and Analysis ; Thinking ; Walking</subject><ispartof>Archives of physical medicine and rehabilitation, 2011-12, Vol.92 (12), p.2028-2033</ispartof><rights>American Congress of Rehabilitation Medicine</rights><rights>2011 American Congress of Rehabilitation Medicine</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-eb7aeb4c24964412a2c6ab15ecf89ca80a17fbeb2463ecb874f31f0bd13999733</citedby><cites>FETCH-LOGICAL-c440t-eb7aeb4c24964412a2c6ab15ecf89ca80a17fbeb2463ecb874f31f0bd13999733</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.apmr.2011.07.004$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25280638$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22133253$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sosnoff, Jacob J., PhD</creatorcontrib><creatorcontrib>Boes, Morgan K., BS</creatorcontrib><creatorcontrib>Sandroff, Brian M., BS</creatorcontrib><creatorcontrib>Socie, Michael J., BS</creatorcontrib><creatorcontrib>Pula, John H., MD</creatorcontrib><creatorcontrib>Motl, Robert W., PhD</creatorcontrib><title>Walking and Thinking in Persons With Multiple Sclerosis Who Vary in Disability</title><title>Archives of physical medicine and rehabilitation</title><addtitle>Arch Phys Med Rehabil</addtitle><description>Abstract Sosnoff JJ, Boes MK, Sandroff BM, Socie MJ, Pula JH, Motl RW. Walking and thinking in persons with multiple sclerosis who vary in disability. Objective To examine the effect of a cognitive task on spatiotemporal parameters of gait in persons with multiple sclerosis (MS) with varying disability. Design Cohort. Setting Testing occurred at a local hospital. Participants Community-living persons (N=78) with MS participated in this investigation. They were divided into 3 groups based on Expanded Disability Status Scale (EDSS) scores: mild (2.0–3.5 EDSS; n=21); moderate (4.0–5.5 EDSS; n=25); and severe (6.0–6.5 EDSS; n=32). Interventions Not applicable. Main Outcome Measures Participants walked at a self-selected pace on an electronic pathway, which recorded spatiotemporal parameters of gait, in 4 separate trials and completed a cognitive task in the last 2 trials. The effect of the cognitive task was quantified as the change in spatiotemporal parameters of gait. Results There was an overall decline in gait with the additive cognitive task. The magnitude of the adverse changes ranged from 1.8% for step length ( P =.02 ) to 12% for gait velocity ( P <.001 ) . Moreover, adverse changes in gait function were greatest in the severe and moderate disability group ( P <.05). Conclusions Persons with MS have impaired walking while doing a cognitive task, and the adverse effect of a cognitive task on walking function is greatest in persons with severe and moderate disability. Difficulty walking while thinking has implications for everyday life and may be related to the risk of falls. Further work is needed to determine whether the adverse effect of an additive cognitive task can be minimized with rehabilitative interventions.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cognition</subject><subject>Cognitive Dysfunction - etiology</subject><subject>Disabled Persons - psychology</subject><subject>Disabled Persons - rehabilitation</subject><subject>Diseases of the osteoarticular system</subject><subject>Female</subject><subject>Gait</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Memory Disorders - etiology</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Miscellaneous. Osteoarticular involvement in other diseases</subject><subject>Multiple Sclerosis - complications</subject><subject>Multiple Sclerosis - psychology</subject><subject>Multiple Sclerosis - rehabilitation</subject><subject>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</subject><subject>Neurology</subject><subject>Physical Medicine and Rehabilitation</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Rehabilitation</subject><subject>Self-Help Devices</subject><subject>Task Performance and Analysis</subject><subject>Thinking</subject><subject>Walking</subject><issn>0003-9993</issn><issn>1532-821X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2LFDEQhoMo7uzqH_AgfRFP3VYl6S8QQdb1A9YP2NX1FtLpaiezmfSYdAvz7007o4IHT6HC81YqTzH2CKFAwOrZptC7bSg4IBZQFwDyDlthKXjecPx6l60AQORt24oTdhrjJpVVKfA-O-EcheClWLEPN9rdWv8t077PrtfW_yqszz5RiKOP2Y2d1tn72U125yi7Mo7CGG26X4_ZFx32C_vKRt1ZZ6f9A3Zv0C7Sw-N5xj6_vrg-f5tffnzz7vzlZW6khCmnrtbUScNlW0mJXHNT6Q5LMkPTGt2AxnroqOOyEmS6ppaDwAG6HkX6Ti3EGXt66LsL4_eZ4qS2NhpyTnsa56haaAChFDKR_ECaNHcMNKhdsNs0uEJQi0a1UYtGtWhUUKukMYUeH9vP3Zb6P5Hf3hLw5AjoaLQbgvbGxr9cyRuoRJO45weOkowfloKKxpI31NtAZlL9aP8_x4t_4sZZb9OLt7SnuBnn4JNmhSpyBepqWfiyb8SUlsnTT8aXpRQ</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Sosnoff, Jacob J., PhD</creator><creator>Boes, Morgan K., BS</creator><creator>Sandroff, Brian M., BS</creator><creator>Socie, Michael J., BS</creator><creator>Pula, John H., MD</creator><creator>Motl, Robert W., PhD</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>Walking and Thinking in Persons With Multiple Sclerosis Who Vary in Disability</title><author>Sosnoff, Jacob J., PhD ; Boes, Morgan K., BS ; Sandroff, Brian M., BS ; Socie, Michael J., BS ; Pula, John H., MD ; Motl, Robert W., PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-eb7aeb4c24964412a2c6ab15ecf89ca80a17fbeb2463ecb874f31f0bd13999733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cognition</topic><topic>Cognitive Dysfunction - etiology</topic><topic>Disabled Persons - psychology</topic><topic>Disabled Persons - rehabilitation</topic><topic>Diseases of the osteoarticular system</topic><topic>Female</topic><topic>Gait</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Memory Disorders - etiology</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Miscellaneous. Osteoarticular involvement in other diseases</topic><topic>Multiple Sclerosis - complications</topic><topic>Multiple Sclerosis - psychology</topic><topic>Multiple Sclerosis - rehabilitation</topic><topic>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</topic><topic>Neurology</topic><topic>Physical Medicine and Rehabilitation</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Rehabilitation</topic><topic>Self-Help Devices</topic><topic>Task Performance and Analysis</topic><topic>Thinking</topic><topic>Walking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sosnoff, Jacob J., PhD</creatorcontrib><creatorcontrib>Boes, Morgan K., BS</creatorcontrib><creatorcontrib>Sandroff, Brian M., BS</creatorcontrib><creatorcontrib>Socie, Michael J., BS</creatorcontrib><creatorcontrib>Pula, John H., MD</creatorcontrib><creatorcontrib>Motl, Robert W., PhD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of physical medicine and rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sosnoff, Jacob J., PhD</au><au>Boes, Morgan K., BS</au><au>Sandroff, Brian M., BS</au><au>Socie, Michael J., BS</au><au>Pula, John H., MD</au><au>Motl, Robert W., PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Walking and Thinking in Persons With Multiple Sclerosis Who Vary in Disability</atitle><jtitle>Archives of physical medicine and rehabilitation</jtitle><addtitle>Arch Phys Med Rehabil</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>92</volume><issue>12</issue><spage>2028</spage><epage>2033</epage><pages>2028-2033</pages><issn>0003-9993</issn><eissn>1532-821X</eissn><coden>APMHAI</coden><abstract>Abstract Sosnoff JJ, Boes MK, Sandroff BM, Socie MJ, Pula JH, Motl RW. Walking and thinking in persons with multiple sclerosis who vary in disability. Objective To examine the effect of a cognitive task on spatiotemporal parameters of gait in persons with multiple sclerosis (MS) with varying disability. Design Cohort. Setting Testing occurred at a local hospital. Participants Community-living persons (N=78) with MS participated in this investigation. They were divided into 3 groups based on Expanded Disability Status Scale (EDSS) scores: mild (2.0–3.5 EDSS; n=21); moderate (4.0–5.5 EDSS; n=25); and severe (6.0–6.5 EDSS; n=32). Interventions Not applicable. Main Outcome Measures Participants walked at a self-selected pace on an electronic pathway, which recorded spatiotemporal parameters of gait, in 4 separate trials and completed a cognitive task in the last 2 trials. The effect of the cognitive task was quantified as the change in spatiotemporal parameters of gait. Results There was an overall decline in gait with the additive cognitive task. The magnitude of the adverse changes ranged from 1.8% for step length ( P =.02 ) to 12% for gait velocity ( P <.001 ) . Moreover, adverse changes in gait function were greatest in the severe and moderate disability group ( P <.05). Conclusions Persons with MS have impaired walking while doing a cognitive task, and the adverse effect of a cognitive task on walking function is greatest in persons with severe and moderate disability. Difficulty walking while thinking has implications for everyday life and may be related to the risk of falls. Further work is needed to determine whether the adverse effect of an additive cognitive task can be minimized with rehabilitative interventions.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>22133253</pmid><doi>10.1016/j.apmr.2011.07.004</doi><tpages>6</tpages></addata></record> |
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| subjects | Adult Biological and medical sciences Cognition Cognitive Dysfunction - etiology Disabled Persons - psychology Disabled Persons - rehabilitation Diseases of the osteoarticular system Female Gait Humans Male Medical sciences Memory Disorders - etiology Middle Aged Miscellaneous Miscellaneous. Osteoarticular involvement in other diseases Multiple Sclerosis - complications Multiple Sclerosis - psychology Multiple Sclerosis - rehabilitation Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Physical Medicine and Rehabilitation Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Rehabilitation Self-Help Devices Task Performance and Analysis Thinking Walking |
| title | Walking and Thinking in Persons With Multiple Sclerosis Who Vary in Disability |
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