Neuropilin-1 expression in cancer and development

Neuropilin (NRP)‐1 is a co‐receptor for vascular endothelial growth factor (VEGF). Preclinical data suggest that blockade of NRP1 suppresses tumour growth by inhibiting angiogenesis, in addition to directly inhibiting tumour cell proliferation in certain models. A humanized monoclonal antibody to NR...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of pathology 2012-01, Vol.226 (1), p.50-60
Hauptverfasser:	Jubb, Adrian M, Strickland, Laura A, Liu, Scot D, Mak, Judy, Schmidt, Maike, Koeppen, Hartmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacology Biological and medical sciences Blotting, Western cancer development Disease Progression Fluorescent Antibody Technique Humans immunofluorescence Immunohistochemistry In Situ Hybridization Investigative techniques, diagnostic techniques (general aspects) Medical sciences Mice Neoplasms - metabolism Neovascularization, Pathologic - metabolism Neovascularization, Physiologic - physiology neuropilin-1 Neuropilin-1 - biosynthesis Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Reverse Transcriptase Polymerase Chain Reaction Transplantation, Heterologous VEGF
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!