Low-Dose D-Methionine and N-Acetyl-L-Cysteine for Protection from Permanent Noise-Induced Hearing Loss in Chinchillas

Objective. Despite efforts at public health awareness and stringent industrial standards for hearing protection, noise-induced hearing loss (NIHL) remains a formidable public health concern. Although many antioxidants have proven to be beneficial in the laboratory for prevention of permanent NIHL, l...

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Veröffentlicht in:	Otolaryngology-head and neck surgery 2011-12, Vol.145 (6), p.999-1006
Hauptverfasser:	Clifford, Royce E., Coleman, John K. M., Balough, Ben J., Liu, Jianzhong, Kopke, Richard D., Jackson, Ronald L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - administration & dosage Animals Auditory Threshold - drug effects Chinchilla Disease Models, Animal Dose-Response Relationship, Drug Drug Administration Schedule Drug Therapy, Combination D‐methionine Evoked Potentials, Auditory, Brain Stem - drug effects Female Hearing Loss, Noise-Induced - drug therapy Hearing Loss, Noise-Induced - prevention & control Injections, Intraperitoneal low‐dose combination Methionine - administration & dosage noise‐induced hearing loss N‐acetyl‐L‐cysteine Random Allocation Reference Values Treatment Outcome
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