Left Ventricular Twist Mechanics in Hypertrophic Cardiomyopathy Assessed by Three-Dimensional Speckle Tracking Echocardiography

Left ventricular (LV) twist represents a phenomenon that links systolic contraction with diastolic relaxation and plays a major role in cardiac physiology; thus, the study of twist mechanics is of particular interest in hypertrophic cardiomyopathy (HC). Three-dimensional speckle tracking echocardiog...

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Veröffentlicht in:The American journal of cardiology 2011-12, Vol.108 (12), p.1788-1795
Hauptverfasser: Urbano Moral, Jose A., MD, Arias Godinez, Jose A., MD, Maron, Martin S., MD, Malik, Rabiya, MD, Eagan, Jacqueline E., BS, Patel, Ayan R., MD, Pandian, Natesa G., MD
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Sprache:eng
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Zusammenfassung:Left ventricular (LV) twist represents a phenomenon that links systolic contraction with diastolic relaxation and plays a major role in cardiac physiology; thus, the study of twist mechanics is of particular interest in hypertrophic cardiomyopathy (HC). Three-dimensional speckle tracking echocardiography (3D-STE) has the potential to overcome the limitations of 2-dimensional imaging and provide a greater understanding of LV twist in HC. We aimed to examine LV twist mechanics in HC using 3D-STE. Echocardiograms from subjects with a diagnosis of HC were examined for 3D-STE analysis. Age- and gender-matched healthy subjects were tested as a control group. Forty patients with HC (age 37 ± 16 years; 42.5% women) and 40 control subjects (age 35 ± 10 years; 42.5% women) were examined. Compared with the controls, the patients with HC showed increased peak LV twist (16.5 ± 4.7° vs 12.0 ± 3.9°, p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2011.07.047