Nucleic acid recognition by the innate immune system

Receptors of the innate immune system recognize conserved microbial features and provide key signals that initiate immune responses. Multiple transmembrane and cytosolic receptors have evolved to recognize RNA and DNA, including members of the Toll-like receptor and RIG-I-like receptor families and...

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Veröffentlicht in:	Annual review of immunology 2011-04, Vol.29 (1), p.185-214
Hauptverfasser:	Barbalat, Roman, Ewald, Sarah E, Mouchess, Maria L, Barton, Gregory M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytosol - chemistry DNA - chemistry Endoplasmic Reticulum - metabolism Humans Immunity, Innate Infection - immunology Lysosomes - metabolism RNA - chemistry Toll-Like Receptors - chemistry Toll-Like Receptors - immunology Toll-Like Receptors - metabolism
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