An overview on genus garcinia: phytochemical and therapeutical aspects
The genus Garcinia belongs to the family Clusiaceae and has been involved in ayurvedic preparations to medicate various pathophysiological disorders. The bioactive molecules like hydroxycitric acid (HCA), flavonoids, terpenes, polysaccharides, procyanidines and polyisoprenylated benzophenone derivat...
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| Veröffentlicht in: | Phytochemistry reviews 2011-09, Vol.10 (3), p.325-351 |
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| creator | Hemshekhar, M. Sunitha, K. Santhosh, M. Sebastin Devaraja, S. Kemparaju, K. Vishwanath, B. S. Niranjana, S. R. Girish, K. S. |
| description | The genus
Garcinia
belongs to the family
Clusiaceae
and has been involved in ayurvedic preparations to medicate various pathophysiological disorders. The bioactive molecules like hydroxycitric acid (HCA), flavonoids, terpenes, polysaccharides, procyanidines and polyisoprenylated benzophenone derivatives like garcinol, xanthochymol and guttiferone isoforms have been isolated from the genus
Garcinia
. The genus has received the attention of pharmaceutical industries due to their immense remedial qualities. The HCA has been known for its hypolipidemic property. The polyisoprenylated benzophenone and xanthone derivatives are known for their antioxidant, apoptotic, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-fungal, anti-ulcer, anti-protozoal, and HAT inhibiting properties. Future studies on the synthesis of therapeutically important products and their analogs and evaluation of their safety and efficacy would be of great interest. Though the genus includes more than 300 species, we have made an effort to conceive the curative qualities of bioactive compounds of selected plants to the best of our knowledge. |
| doi_str_mv | 10.1007/s11101-011-9207-3 |
| format | Article |
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Garcinia
belongs to the family
Clusiaceae
and has been involved in ayurvedic preparations to medicate various pathophysiological disorders. The bioactive molecules like hydroxycitric acid (HCA), flavonoids, terpenes, polysaccharides, procyanidines and polyisoprenylated benzophenone derivatives like garcinol, xanthochymol and guttiferone isoforms have been isolated from the genus
Garcinia
. The genus has received the attention of pharmaceutical industries due to their immense remedial qualities. The HCA has been known for its hypolipidemic property. The polyisoprenylated benzophenone and xanthone derivatives are known for their antioxidant, apoptotic, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-fungal, anti-ulcer, anti-protozoal, and HAT inhibiting properties. Future studies on the synthesis of therapeutically important products and their analogs and evaluation of their safety and efficacy would be of great interest. Though the genus includes more than 300 species, we have made an effort to conceive the curative qualities of bioactive compounds of selected plants to the best of our knowledge.</description><identifier>ISSN: 1568-7767</identifier><identifier>EISSN: 1572-980X</identifier><identifier>DOI: 10.1007/s11101-011-9207-3</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Antioxidants ; Antiviral agents ; Apoptosis ; Benzophenone ; Bioactive compounds ; Biochemistry ; Biological activity ; Biomedical and Life Sciences ; Chemistry/Food Science ; Clusiaceae ; Derivatives ; Flavonoids ; Fungicides ; Garcinia ; Inflammation ; Isoforms ; Life Sciences ; Organic Chemistry ; Pharmaceutical industry ; Pharmaceuticals ; Plant Genetics and Genomics ; Plant Sciences ; Plants (botany) ; Polysaccharides ; Product safety ; Reviews ; Saccharides ; Terpenes</subject><ispartof>Phytochemistry reviews, 2011-09, Vol.10 (3), p.325-351</ispartof><rights>Springer Science+Business Media B.V. 2011</rights><rights>Phytochemistry Reviews is a copyright of Springer, (2011). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c348t-cb2af10ef224eaa26b921cddb15ed096601db77df7d77b85ce712e659258d9633</citedby><cites>FETCH-LOGICAL-c348t-cb2af10ef224eaa26b921cddb15ed096601db77df7d77b85ce712e659258d9633</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11101-011-9207-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11101-011-9207-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Hemshekhar, M.</creatorcontrib><creatorcontrib>Sunitha, K.</creatorcontrib><creatorcontrib>Santhosh, M. Sebastin</creatorcontrib><creatorcontrib>Devaraja, S.</creatorcontrib><creatorcontrib>Kemparaju, K.</creatorcontrib><creatorcontrib>Vishwanath, B. S.</creatorcontrib><creatorcontrib>Niranjana, S. R.</creatorcontrib><creatorcontrib>Girish, K. S.</creatorcontrib><title>An overview on genus garcinia: phytochemical and therapeutical aspects</title><title>Phytochemistry reviews</title><addtitle>Phytochem Rev</addtitle><description>The genus
Garcinia
belongs to the family
Clusiaceae
and has been involved in ayurvedic preparations to medicate various pathophysiological disorders. The bioactive molecules like hydroxycitric acid (HCA), flavonoids, terpenes, polysaccharides, procyanidines and polyisoprenylated benzophenone derivatives like garcinol, xanthochymol and guttiferone isoforms have been isolated from the genus
Garcinia
. The genus has received the attention of pharmaceutical industries due to their immense remedial qualities. The HCA has been known for its hypolipidemic property. The polyisoprenylated benzophenone and xanthone derivatives are known for their antioxidant, apoptotic, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-fungal, anti-ulcer, anti-protozoal, and HAT inhibiting properties. Future studies on the synthesis of therapeutically important products and their analogs and evaluation of their safety and efficacy would be of great interest. Though the genus includes more than 300 species, we have made an effort to conceive the curative qualities of bioactive compounds of selected plants to the best of our knowledge.</description><subject>Antioxidants</subject><subject>Antiviral agents</subject><subject>Apoptosis</subject><subject>Benzophenone</subject><subject>Bioactive compounds</subject><subject>Biochemistry</subject><subject>Biological activity</subject><subject>Biomedical and Life Sciences</subject><subject>Chemistry/Food Science</subject><subject>Clusiaceae</subject><subject>Derivatives</subject><subject>Flavonoids</subject><subject>Fungicides</subject><subject>Garcinia</subject><subject>Inflammation</subject><subject>Isoforms</subject><subject>Life Sciences</subject><subject>Organic Chemistry</subject><subject>Pharmaceutical industry</subject><subject>Pharmaceuticals</subject><subject>Plant Genetics and Genomics</subject><subject>Plant Sciences</subject><subject>Plants (botany)</subject><subject>Polysaccharides</subject><subject>Product safety</subject><subject>Reviews</subject><subject>Saccharides</subject><subject>Terpenes</subject><issn>1568-7767</issn><issn>1572-980X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kEFLwzAUx4MoOKcfwFvBg6doXrokjbcxnAoDLwreQpq-bh1bWpN2sm9vSwVB8PQej9__z-NHyDWwO2BM3UcAYEAZANWcKZqekAkIxanO2MfpsMuMKiXVObmIccsYByn4hCznPqkPGA4VfiW1T9bou5isbXCVr-xD0myObe02uK-c3SXWF0m7wWAb7NrxEht0bbwkZ6XdRbz6mVPyvnx8WzzT1evTy2K-oi6dZS11ObclMCw5n6G1XOaagyuKHAQWTEvJoMiVKkpVKJVnwqECjlJoLrJCyzSdktuxtwn1Z4exNfsqOtztrMe6i0YzBZkSnPXkzR9yW3fB988ZzoWeAYhM9hSMlAt1jAFL04Rqb8PRADODWDOKNb1YM4g1ww98zMSe9WsMv83_h74BMIZ61g</recordid><startdate>20110901</startdate><enddate>20110901</enddate><creator>Hemshekhar, M.</creator><creator>Sunitha, K.</creator><creator>Santhosh, M. Sebastin</creator><creator>Devaraja, S.</creator><creator>Kemparaju, K.</creator><creator>Vishwanath, B. S.</creator><creator>Niranjana, S. R.</creator><creator>Girish, K. S.</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X2</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M0K</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>M7N</scope></search><sort><creationdate>20110901</creationdate><title>An overview on genus garcinia: phytochemical and therapeutical aspects</title><author>Hemshekhar, M. ; Sunitha, K. ; Santhosh, M. Sebastin ; Devaraja, S. ; Kemparaju, K. ; Vishwanath, B. S. ; Niranjana, S. R. ; Girish, K. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c348t-cb2af10ef224eaa26b921cddb15ed096601db77df7d77b85ce712e659258d9633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Antioxidants</topic><topic>Antiviral agents</topic><topic>Apoptosis</topic><topic>Benzophenone</topic><topic>Bioactive compounds</topic><topic>Biochemistry</topic><topic>Biological activity</topic><topic>Biomedical and Life Sciences</topic><topic>Chemistry/Food Science</topic><topic>Clusiaceae</topic><topic>Derivatives</topic><topic>Flavonoids</topic><topic>Fungicides</topic><topic>Garcinia</topic><topic>Inflammation</topic><topic>Isoforms</topic><topic>Life Sciences</topic><topic>Organic Chemistry</topic><topic>Pharmaceutical industry</topic><topic>Pharmaceuticals</topic><topic>Plant Genetics and Genomics</topic><topic>Plant Sciences</topic><topic>Plants (botany)</topic><topic>Polysaccharides</topic><topic>Product safety</topic><topic>Reviews</topic><topic>Saccharides</topic><topic>Terpenes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hemshekhar, M.</creatorcontrib><creatorcontrib>Sunitha, K.</creatorcontrib><creatorcontrib>Santhosh, M. Sebastin</creatorcontrib><creatorcontrib>Devaraja, S.</creatorcontrib><creatorcontrib>Kemparaju, K.</creatorcontrib><creatorcontrib>Vishwanath, B. S.</creatorcontrib><creatorcontrib>Niranjana, S. R.</creatorcontrib><creatorcontrib>Girish, K. 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Sebastin</au><au>Devaraja, S.</au><au>Kemparaju, K.</au><au>Vishwanath, B. S.</au><au>Niranjana, S. R.</au><au>Girish, K. S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An overview on genus garcinia: phytochemical and therapeutical aspects</atitle><jtitle>Phytochemistry reviews</jtitle><stitle>Phytochem Rev</stitle><date>2011-09-01</date><risdate>2011</risdate><volume>10</volume><issue>3</issue><spage>325</spage><epage>351</epage><pages>325-351</pages><issn>1568-7767</issn><eissn>1572-980X</eissn><abstract>The genus
Garcinia
belongs to the family
Clusiaceae
and has been involved in ayurvedic preparations to medicate various pathophysiological disorders. The bioactive molecules like hydroxycitric acid (HCA), flavonoids, terpenes, polysaccharides, procyanidines and polyisoprenylated benzophenone derivatives like garcinol, xanthochymol and guttiferone isoforms have been isolated from the genus
Garcinia
. The genus has received the attention of pharmaceutical industries due to their immense remedial qualities. The HCA has been known for its hypolipidemic property. The polyisoprenylated benzophenone and xanthone derivatives are known for their antioxidant, apoptotic, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-fungal, anti-ulcer, anti-protozoal, and HAT inhibiting properties. Future studies on the synthesis of therapeutically important products and their analogs and evaluation of their safety and efficacy would be of great interest. Though the genus includes more than 300 species, we have made an effort to conceive the curative qualities of bioactive compounds of selected plants to the best of our knowledge.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><doi>10.1007/s11101-011-9207-3</doi><tpages>27</tpages></addata></record> |
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| subjects | Antioxidants Antiviral agents Apoptosis Benzophenone Bioactive compounds Biochemistry Biological activity Biomedical and Life Sciences Chemistry/Food Science Clusiaceae Derivatives Flavonoids Fungicides Garcinia Inflammation Isoforms Life Sciences Organic Chemistry Pharmaceutical industry Pharmaceuticals Plant Genetics and Genomics Plant Sciences Plants (botany) Polysaccharides Product safety Reviews Saccharides Terpenes |
| title | An overview on genus garcinia: phytochemical and therapeutical aspects |
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