Multiple inhibitory actions of lidocaine on Torpedo nicotinic acetylcholine receptors transplanted to Xenopus oocytes

J. Neurochem. (2011) 117, 1009–1019. Lidocaine is a local anaesthetic that blocks sodium channels, but also inhibits several ligand‐gated ion‐channels. The aim of this work was to unravel the mechanisms by which lidocaine blocks Torpedo nicotinic receptors transplanted to Xenopus oocytes. Acetylchol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurochemistry 2011-06, Vol.117 (6), p.1009-1019
Hauptverfasser:	Alberola‐Die, Armando, Martinez‐Pinna, Juan, González‐Ros, José Manuel, Ivorra, Isabel, Morales, Andrés
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Anesthetics, Local - pharmacology Animals Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide - pharmacology Biological and medical sciences Brain Cell receptors Cell structures and functions Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Dose-Response Relationship, Drug Drug Synergism Edrophonium - pharmacology Female Fundamental and applied biological sciences. Psychology In Vitro Techniques Inhibitor drugs Ion Channel Gating lidocaine Lidocaine - analogs & derivatives Lidocaine - pharmacology local anaesthetics Membrane Potentials - drug effects microtransplantation Molecular and cellular biology Monoamines receptors (catecholamine, serotonine, histamine, acetylcholine) Neurochemistry Neurotransmitters nicotinic acetylcholine receptors Nicotinic Antagonists - pharmacology Oocytes - drug effects Oocytes - physiology Pharmacology QX‐314 Receptors, Nicotinic - physiology Torpedo Vertebrates: nervous system and sense organs Xenopus Xenopus laevis Xenopus oocytes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!