Amino acids exhibit anti-inflammatory effects in human monocytic leukemia cell line, THP-1 cells

Objective The elemental diet is one of the effective therapies for inflammatory bowel disease. However, the mechanism remains unclear, and there have never been reports about the inhibitory effects of amino acids in human monocytes/macrophages. We investigated the inhibitory effects of amino acids o...

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Veröffentlicht in:	Inflammation research 2011-11, Vol.60 (11), p.1013-1019
Hauptverfasser:	Hasegawa, Shunji, Ichiyama, Takashi, Sonaka, Ichiro, Ohsaki, Ayami, Hirano, Reiji, Haneda, Yasuhiro, Fukano, Reiji, Hara, Masami, Furukawa, Susumu
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergology Amino Acids - metabolism Amino Acids - pharmacology Anti-Inflammatory Agents - pharmacology Biomedical and Life Sciences Biomedicine Cytokines - metabolism Dermatology Dose-Response Relationship, Drug Humans Immunology Inflammation - drug therapy Intercellular Adhesion Molecule-1 - biosynthesis Interleukin-8 - metabolism Leukemia, Monocytic, Acute - drug therapy Leukemia, Monocytic, Acute - metabolism Leukocytes, Mononuclear - cytology Macrophages - metabolism Neurology NF-kappa B - metabolism Original Research Paper Pharmacology/Toxicology Phosphorylation Polymerase Chain Reaction Rheumatology Tumor Necrosis Factor-alpha - metabolism
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