Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trial

Summary Background In May 2011, an outbreak of Shiga toxin-producing enterohaemorrhagic E coli O104:H4 in northern Germany led to a high proportion of patients developing post-enteritis haemolytic uraemic syndrome and thrombotic microangiopathy that were unresponsive to therapeutic plasma exchange o...

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Veröffentlicht in:	The Lancet (British edition) 2011-09, Vol.378 (9797), p.1166-1173
Hauptverfasser:	Greinacher, Andreas, Prof, Friesecke, Sigrun, MD, Abel, Peter, MD, Dressel, Alexander, MD, Stracke, Sylvia, MD, Fiene, Michael, MD, Ernst, Friedlinde, MD, Selleng, Kathleen, MD, Weissenborn, Karin, MD, Schmidt, Bernhard MW, MD, Schiffer, Mario, MD, Felix, Stephan B, Prof, Lerch, Markus M, Prof, Kielstein, Jan T, MD, Mayerle, Julia, Prof
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult antibodies Aphasia Bacterial diseases Bacterial infections Biological and medical sciences Delirium Disease E coli enteritis Enterohemorrhagic Escherichia coli Escherichia coli Escherichia coli Infections - complications Female General aspects Hematologic and hematopoietic diseases Hemolytic-Uremic Syndrome - complications Humans immunoglobulin G Immunoglobulin G - blood Immunosorbent Techniques Internal Medicine intravenous injection Male Medical sciences Mental disorders microangiopathy Middle Aged Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Nervous System Diseases - microbiology Nervous System Diseases - therapy Neurological complications pathogenesis patients Plasma Platelet diseases and coagulopathies Renal failure Renal function Respiratory function seizures Shiga-Toxigenic Escherichia coli therapeutics Toxins Ventilation
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