Multivalent calixarene-based C-fucosyl derivative: a new Pseudomonas aeruginosa biofilm inhibitor

The first example of multivalent conjugate in which four α- l- C-fucosyl units are clustered by means of a calix[4]arene platform was designed as a new potential Pseudomonas aeruginosa biofilm inhibitor. The anti-biofilm activity of the synthesized compound ( 6) against PAO1 strain was assayed and i...

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Veröffentlicht in:	Tetrahedron letters 2011-11, Vol.52 (44), p.5831-5834
Hauptverfasser:	Consoli, Grazia M.L., Granata, Giuseppe, Cafiso, Viviana, Stefani, Stefania, Geraci, Corrada
Format:	Artikel
Sprache:	eng
Schlagworte:	Alicyclic compounds Alicyclic compounds, terpenoids, prostaglandins, steroids Biofilms C-Fucosyl derivative Calixarene Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides Carbohydrates. Nucleosides and nucleotides Chemistry Conjugates Derivatives Exact sciences and technology Fucose Inhibition biofilm assay Inhibitors Multivalency Organic chemistry Platforms Preparations and properties Pseudomonas aeruginosa Tetrahedrons
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