Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells

Phytochemicals in some foods are a potential source of bioactive safe compounds for cancer chemoprevention and suppression of tumor initiation, promotion, and metastasis. In the present study, we evaluated hot water (HWE), microwaved 50% ethanol (MWE), acidic (ACE), and alkaline (AKE) extracts of th...

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Veröffentlicht in:	Food & function 2011-06, Vol.2 (6), p.348-356
Hauptverfasser:	Kim, Sung Phil, Kang, Mi Young, Choi, Yong Hee, Kim, Jae Ho, Nam, Seok Hyun, Friedman, Mendel
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricales - chemistry Apoptosis Apoptosis - drug effects Basidiocarps Biological Products - pharmacology Blotting, Western Cancer Carbohydrates Caspase 3 - metabolism Caspase 8 - metabolism Caspase 9 - metabolism Caspase-3 Caspase-8 Caspase-9 Cell culture Cell proliferation Cell Proliferation - drug effects Cell Survival - drug effects Chemoprevention - methods Cytotoxicity DNA DNA Fragmentation - drug effects Ethanol Flow Cytometry Food Humans Membrane potential Membrane Potential, Mitochondrial - drug effects Metastases Minerals Mitochondria Mitochondria - drug effects Mitochondria - metabolism Mitochondrial DNA Monocytic leukemia Powder Signal Transduction sporocarps Tumors U937 Cells
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