Tyrosine kinase inhibitor insensitivity of non‐cycling CD34+ human acute myeloid leukaemia cells with FMS‐like tyrosine kinase 3 mutations

Summary The efficacy of tyrosine kinase (TK) inhibitors on non‐cycling acute myeloid leukaemia (AML) cells, previously shown to have potent tumourigenic potential, is unknown. This pilot study describes the first attempt to characterize non‐cycling cells from a small series of human FMS‐like tyrosin...

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Veröffentlicht in:British journal of haematology 2011-08, Vol.154 (4), p.457-465
Hauptverfasser: Alvares, Caroline L., Schenk, Tino, Hulkki, Sanna, Min, Toon, Vijayaraghavan, Gowri, Yeung, Jenny, Gonzalez, David, So, Chi W. E., Greaves, Mel, Titley, Ian, Bartolovic, Kerol, Morgan, Gareth
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Sprache:eng
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