Assessing the factors responsible for ionic liquid toxicity to aquatic organisms via quantitative structure–property relationship modeling

Experimental data on the aquatic toxicity of a range of ionic liquids (ILs) on two aquatic organisms were presented. Microbial toxicity was estimated using a standard Microtox Acute Toxicity test system to determine the effective concentration at 50% to the marine bacterium Vibrio fischeri. Toxicity to a freshwater crustacean was determined using 48 h acute toxicity bioassays. The data were used to build a predictive toxicity model based upon quantitative structure-property relationship modeling (QSPR) methods. The model was used to elucidate the chemical and structural factors that governed the toxicity of these compounds to V. fischeri and D. magna.