Ethanol withdrawal activates nitric oxide–producing neurons in anxiety-related brain areas

Abstract The present study investigated whether nitric oxide (NO)–producing neurons localized in brain areas related to anxiety are also activated after ethanol withdrawal. Male Wistar rats were subjected to an oral ethanol self-administration procedure, in which they were offered 6–8% (vol/vol) eth...

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Veröffentlicht in:	Alcohol (Fayetteville, N.Y.) N.Y.), 2011-11, Vol.45 (7), p.641-652
Hauptverfasser:	Bonassoli, Vivian Taciany, Milani, Humberto, de Oliveira, Rúbia Maria Weffort
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism Amygdala Animals Anxiety Anxiety - physiopathology Autonomic nervous system Brain Brain - physiopathology dorsal raphe nucleus Drug self-administration Emotions Ethanol Ethanol - administration & dosage Ethanol withdrawal Exploratory behavior Fos protein Histochemistry Hypothalamus Immunohistochemistry Male NADPH dehydrogenase Neurology Neurons Neurons - physiology Nitric oxide Nitric Oxide - biosynthesis Paraventricular Hypothalamic Nucleus - physiopathology Paraventricular nucleus Periaqueductal Gray - physiopathology Periaqueductal gray area Psychiatry Raphe Nuclei - physiopathology Rats Rats, Wistar Rodents Substance Withdrawal Syndrome - physiopathology
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