Thermoelectric method for sequencing DNA

This study describes a novel, thermoelectric method for DNA sequencing in a microfluidic device. The method measures the heat released when DNA polymerase inserts a deoxyribonucleoside triphosphate into a primed DNA template. The study describes the principle of operation of a laminar flow microflui...

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Veröffentlicht in:	Lab on a chip 2011-05, Vol.11 (10), p.1761-1769
Hauptverfasser:	Nestorova, Gergana G, Guilbeau, Eric J
Format:	Artikel
Sprache:	eng
Schlagworte:	Conserved sequence DNA - chemistry DNA Primers - chemistry DNA-Directed DNA Polymerase - metabolism Microfluidic Analytical Techniques - instrumentation Microfluidic Analytical Techniques - methods Sequence Analysis, DNA - instrumentation Sequence Analysis, DNA - methods Temperature
Online-Zugang:	Volltext
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