Cellular uptake, cytotoxicity, and ROS generation with silica/conducting polymer core/shell nanospheres

Abstract The cellular response to conducting polymer (CP) nanospheres with similar physical properties was evaluated by in vitro cellular uptake and cytotoxicity in mouse macrophage RAW 264.7 and rat pheochromocytoma PC-12 cells. Four different CPs (polythiophene, poly(3,4-ethylenedioxythiophene), p...

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Veröffentlicht in:	Biomaterials 2011-10, Vol.32 (29), p.7217-7225
Hauptverfasser:	Jeong, Yoon Seon, Oh, Wan-Kyu, Kim, Sojin, Jang, Jyongsik
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Biocompatible Materials - chemistry Cell Line Cell Survival Cell viability Conducting polymer Core shell nanosphere Cytotoxicity Dentistry Humans L-Lactate Dehydrogenase - metabolism Macrophages - cytology Macrophages - metabolism Mice Nanospheres - chemistry Nanospheres - toxicity Nanospheres - ultrastructure Particle Size PC12 Cells Polymers - chemistry Rats Reactive oxygen species Reactive Oxygen Species - metabolism Silicon Dioxide - chemistry
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