A nanobiohybrid complex of recombinant baculovirus and Tat/DNA nanoparticles for delivery of Ang-1 transgene in myocardial infarction therapy

Abstract The study aims to design a new gene delivery method utilizing the complementary strengths of baculovirus, such as relatively high transduction efficiency and easy scale-up, and non-viral nanodelivery systems, such as low immunogenicity. This formulation was developed by generating a self as...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomaterials 2011-11, Vol.32 (32), p.8304-8318
Hauptverfasser:	Paul, Arghya, Binsalamah, Zyad M, Khan, Afshan A, Abbasia, Sana, Elias, Cynthia B, Shum-Tim, Dominique, Prakash, Satya
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Angiopoietin-1 - genetics Angiopoietin-1 - therapeutic use Animals Baculoviridae - genetics Baculovirus Chemotaxis Dentistry Disease Models, Animal DNA - metabolism Encapsulation Gene Products, tat - metabolism Gene therapy Genetic Therapy Heart Function Tests Human Umbilical Vein Endothelial Cells - cytology Human Umbilical Vein Endothelial Cells - metabolism Humans Microencapsulation Mitosis Myocardial angiogenesis Myocardial Infarction - physiopathology Myocardial Infarction - therapy Myocardium - pathology Nanoparticle Nanoparticles - chemistry Neovascularization, Physiologic Organogenesis Rats Recombination, Genetic - genetics Transduction, Genetic Transgenes - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!