Source of infection in young infants hospitalized with Bordetella pertussis
Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism. To determine the source of Pertussis infection in infants aged six months or less in Chile. Twenty six household contacts of 10 young infants hospitalized with confirmed P...
Gespeichert in:
| Veröffentlicht in: | Revista medíca de Chile 2011-04, Vol.139 (4), p.448-454 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | spa |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 454 |
|---|---|
| container_issue | 4 |
| container_start_page | 448 |
| container_title | Revista medíca de Chile |
| container_volume | 139 |
| creator | Perret, Cecilia Viviani, Tamara Peña, Anamaría Abarca, Katia Ferrés, Marcela |
| description | Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism.
To determine the source of Pertussis infection in infants aged six months or less in Chile.
Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polymerase chain reaction (PCR). Clinical and demographic data were analyzed.
Respiratory symptoms were present in 20 (77%) contacts, being cough the most common. Pertussis cases were identified in every household and in 18 (72%) of the household members. four members with B.pertussis were asymptomatic. Source of infection was identified in 80% (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PCR and their cough duration was significantly shorter compared to primary cases with negative PCR.
B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants. |
| doi_str_mv | 10.4067/S0034-98872011000400005 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_907171357</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>886916099</sourcerecordid><originalsourceid>FETCH-LOGICAL-p172t-a814a2b7b93ccf8895b2417e24f08c79e0d9b6f22ce520ef625cfc2b1d3438463</originalsourceid><addsrcrecordid>eNqFkMtOwzAURC0EoqXwC-Adq8D1I34soSoPUYlFYR0ljk2N0jjEjlD5elLRrlmM7mh0dDUahK4I3HAQ8nYFwHimlZIUCAEAPgryIzQFSWQmiGDHoz9AE3QW4ycAlYKoUzShRElNFJ2il1UYemNxcNi3zprkQzs6vA1D-7GLyjZFvA6x86ls_I-t8bdPa3wf-tom2zQl7myfhhh9PEcnrmyivdjfGXp_WLzNn7Ll6-Pz_G6ZdUTSlJWK8JJWstLMGKeUzivKibSUO1BGagu1roSj1NicgnWC5sYZWpGacaa4YDN0_fe368PXYGMqNj6aXZfWhiEWercBYbn8l1RKaCJA65G83JNDtbF10fV-U_bb4rAU-wXEu2x1</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>886916099</pqid></control><display><type>article</type><title>Source of infection in young infants hospitalized with Bordetella pertussis</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Perret, Cecilia ; Viviani, Tamara ; Peña, Anamaría ; Abarca, Katia ; Ferrés, Marcela</creator><creatorcontrib>Perret, Cecilia ; Viviani, Tamara ; Peña, Anamaría ; Abarca, Katia ; Ferrés, Marcela</creatorcontrib><description>Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism.
To determine the source of Pertussis infection in infants aged six months or less in Chile.
Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polymerase chain reaction (PCR). Clinical and demographic data were analyzed.
Respiratory symptoms were present in 20 (77%) contacts, being cough the most common. Pertussis cases were identified in every household and in 18 (72%) of the household members. four members with B.pertussis were asymptomatic. Source of infection was identified in 80% (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PCR and their cough duration was significantly shorter compared to primary cases with negative PCR.
B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants.</description><identifier>ISSN: 0034-9887</identifier><identifier>EISSN: 0717-6163</identifier><identifier>DOI: 10.4067/S0034-98872011000400005</identifier><identifier>PMID: 21879182</identifier><language>spa</language><publisher>Chile</publisher><subject>Adolescent ; Adult ; Aged ; Bordetella pertussis ; Bordetella pertussis - genetics ; Bordetella pertussis - isolation & purification ; Child ; Child, Preschool ; Chile ; Contact Tracing ; Family Characteristics ; Female ; Humans ; Infant ; Male ; Middle Aged ; Polymerase Chain Reaction ; Risk Factors ; Vaccination ; Whooping Cough - diagnosis ; Whooping Cough - transmission ; Young Adult</subject><ispartof>Revista medíca de Chile, 2011-04, Vol.139 (4), p.448-454</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21879182$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Perret, Cecilia</creatorcontrib><creatorcontrib>Viviani, Tamara</creatorcontrib><creatorcontrib>Peña, Anamaría</creatorcontrib><creatorcontrib>Abarca, Katia</creatorcontrib><creatorcontrib>Ferrés, Marcela</creatorcontrib><title>Source of infection in young infants hospitalized with Bordetella pertussis</title><title>Revista medíca de Chile</title><addtitle>Rev Med Chil</addtitle><description>Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism.
To determine the source of Pertussis infection in infants aged six months or less in Chile.
Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polymerase chain reaction (PCR). Clinical and demographic data were analyzed.
Respiratory symptoms were present in 20 (77%) contacts, being cough the most common. Pertussis cases were identified in every household and in 18 (72%) of the household members. four members with B.pertussis were asymptomatic. Source of infection was identified in 80% (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PCR and their cough duration was significantly shorter compared to primary cases with negative PCR.
B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Bordetella pertussis</subject><subject>Bordetella pertussis - genetics</subject><subject>Bordetella pertussis - isolation & purification</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Chile</subject><subject>Contact Tracing</subject><subject>Family Characteristics</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Polymerase Chain Reaction</subject><subject>Risk Factors</subject><subject>Vaccination</subject><subject>Whooping Cough - diagnosis</subject><subject>Whooping Cough - transmission</subject><subject>Young Adult</subject><issn>0034-9887</issn><issn>0717-6163</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAURC0EoqXwC-Adq8D1I34soSoPUYlFYR0ljk2N0jjEjlD5elLRrlmM7mh0dDUahK4I3HAQ8nYFwHimlZIUCAEAPgryIzQFSWQmiGDHoz9AE3QW4ycAlYKoUzShRElNFJ2il1UYemNxcNi3zprkQzs6vA1D-7GLyjZFvA6x86ls_I-t8bdPa3wf-tom2zQl7myfhhh9PEcnrmyivdjfGXp_WLzNn7Ll6-Pz_G6ZdUTSlJWK8JJWstLMGKeUzivKibSUO1BGagu1roSj1NicgnWC5sYZWpGacaa4YDN0_fe368PXYGMqNj6aXZfWhiEWercBYbn8l1RKaCJA65G83JNDtbF10fV-U_bb4rAU-wXEu2x1</recordid><startdate>201104</startdate><enddate>201104</enddate><creator>Perret, Cecilia</creator><creator>Viviani, Tamara</creator><creator>Peña, Anamaría</creator><creator>Abarca, Katia</creator><creator>Ferrés, Marcela</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>7QL</scope><scope>C1K</scope></search><sort><creationdate>201104</creationdate><title>Source of infection in young infants hospitalized with Bordetella pertussis</title><author>Perret, Cecilia ; Viviani, Tamara ; Peña, Anamaría ; Abarca, Katia ; Ferrés, Marcela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p172t-a814a2b7b93ccf8895b2417e24f08c79e0d9b6f22ce520ef625cfc2b1d3438463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Bordetella pertussis</topic><topic>Bordetella pertussis - genetics</topic><topic>Bordetella pertussis - isolation & purification</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Chile</topic><topic>Contact Tracing</topic><topic>Family Characteristics</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Polymerase Chain Reaction</topic><topic>Risk Factors</topic><topic>Vaccination</topic><topic>Whooping Cough - diagnosis</topic><topic>Whooping Cough - transmission</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Perret, Cecilia</creatorcontrib><creatorcontrib>Viviani, Tamara</creatorcontrib><creatorcontrib>Peña, Anamaría</creatorcontrib><creatorcontrib>Abarca, Katia</creatorcontrib><creatorcontrib>Ferrés, Marcela</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Revista medíca de Chile</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Perret, Cecilia</au><au>Viviani, Tamara</au><au>Peña, Anamaría</au><au>Abarca, Katia</au><au>Ferrés, Marcela</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Source of infection in young infants hospitalized with Bordetella pertussis</atitle><jtitle>Revista medíca de Chile</jtitle><addtitle>Rev Med Chil</addtitle><date>2011-04</date><risdate>2011</risdate><volume>139</volume><issue>4</issue><spage>448</spage><epage>454</epage><pages>448-454</pages><issn>0034-9887</issn><eissn>0717-6163</eissn><abstract>Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism.
To determine the source of Pertussis infection in infants aged six months or less in Chile.
Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polymerase chain reaction (PCR). Clinical and demographic data were analyzed.
Respiratory symptoms were present in 20 (77%) contacts, being cough the most common. Pertussis cases were identified in every household and in 18 (72%) of the household members. four members with B.pertussis were asymptomatic. Source of infection was identified in 80% (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PCR and their cough duration was significantly shorter compared to primary cases with negative PCR.
B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants.</abstract><cop>Chile</cop><pmid>21879182</pmid><doi>10.4067/S0034-98872011000400005</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0034-9887 |
| ispartof | Revista medíca de Chile, 2011-04, Vol.139 (4), p.448-454 |
| issn | 0034-9887 0717-6163 |
| language | spa |
| recordid | cdi_proquest_miscellaneous_907171357 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Adult Aged Bordetella pertussis Bordetella pertussis - genetics Bordetella pertussis - isolation & purification Child Child, Preschool Chile Contact Tracing Family Characteristics Female Humans Infant Male Middle Aged Polymerase Chain Reaction Risk Factors Vaccination Whooping Cough - diagnosis Whooping Cough - transmission Young Adult |
| title | Source of infection in young infants hospitalized with Bordetella pertussis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T19%3A36%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Source%20of%20infection%20in%20young%20infants%20hospitalized%20with%20Bordetella%20pertussis&rft.jtitle=Revista%20med%C3%ADca%20de%20Chile&rft.au=Perret,%20Cecilia&rft.date=2011-04&rft.volume=139&rft.issue=4&rft.spage=448&rft.epage=454&rft.pages=448-454&rft.issn=0034-9887&rft.eissn=0717-6163&rft_id=info:doi/10.4067/S0034-98872011000400005&rft_dat=%3Cproquest_pubme%3E886916099%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=886916099&rft_id=info:pmid/21879182&rfr_iscdi=true |