A Rare Masquerader of Lung Cancer: Nonsecretory Multiple Myeloma with Plasmacytoma of Bone Presenting as Acute Kidney Injury
Multiple myeloma (MM) is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells which produce immunglobulins. If a monoclonal spike is not found in serum or urine but the patient has clinical findings and bone marrow plasma cell infiltration suggestive of MM,...
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| Veröffentlicht in: | Internal Medicine 2010, Vol.49(19), pp.2133-2135 |
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| container_issue | 19 |
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| container_title | Internal Medicine |
| container_volume | 49 |
| creator | Guney, Ibrahim Solak, Yalcin Atalay, Huseyin Altintepe, Lutfullah Tonbul, H. Zeki |
| description | Multiple myeloma (MM) is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells which produce immunglobulins. If a monoclonal spike is not found in serum or urine but the patient has clinical findings and bone marrow plasma cell infiltration suggestive of MM, then the patient may have a rare subtype known as nonsecretory multiple myeloma (NSMM). Here, we describe a rare case of NSMM with plasmacytoma of bone who presented with severe hypercalcemia, acute kidney injury and a large thoracal mass on chest X-ray masquerading as lung cancer. |
| doi_str_mv | 10.2169/internalmedicine.49.3709 |
| format | Article |
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Here, we describe a rare case of NSMM with plasmacytoma of bone who presented with severe hypercalcemia, acute kidney injury and a large thoracal mass on chest X-ray masquerading as lung cancer.</description><identifier>ISSN: 0918-2918</identifier><identifier>ISSN: 1349-7235</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.49.3709</identifier><identifier>PMID: 20930442</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>acute kidney injury ; Acute Kidney Injury - etiology ; Adult ; Bone cancer ; Bone marrow ; Bone mass ; Bone Neoplasms - complications ; Bone Neoplasms - diagnosis ; Bone Neoplasms - diagnostic imaging ; Cell lineage ; Cell proliferation ; Chest ; Diagnosis, Differential ; Humans ; Hypercalcemia ; Injuries ; Ionizing radiation ; Kidney ; Lung cancer ; Lung Neoplasms - diagnosis ; Lymphocytes B ; Male ; masquerader ; Multiple myeloma ; Multiple Myeloma - complications ; Multiple Myeloma - diagnosis ; Multiple Myeloma - diagnostic imaging ; nonsecretory multiple myeloma ; Plasma cells ; Plasmacytoma ; Plasmacytoma - complications ; Plasmacytoma - diagnosis ; Plasmacytoma - diagnostic imaging ; plasmacytoma of bone ; Radiography ; Urine</subject><ispartof>Internal Medicine, 2010, Vol.49(19), pp.2133-2135</ispartof><rights>2010 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c503t-853ab1e1170bbfab3dc8069e2320df3e788901dc1dc21dbbbb57583107570b233</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20930442$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guney, Ibrahim</creatorcontrib><creatorcontrib>Solak, Yalcin</creatorcontrib><creatorcontrib>Atalay, Huseyin</creatorcontrib><creatorcontrib>Altintepe, Lutfullah</creatorcontrib><creatorcontrib>Tonbul, H. Zeki</creatorcontrib><title>A Rare Masquerader of Lung Cancer: Nonsecretory Multiple Myeloma with Plasmacytoma of Bone Presenting as Acute Kidney Injury</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>Multiple myeloma (MM) is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells which produce immunglobulins. If a monoclonal spike is not found in serum or urine but the patient has clinical findings and bone marrow plasma cell infiltration suggestive of MM, then the patient may have a rare subtype known as nonsecretory multiple myeloma (NSMM). Here, we describe a rare case of NSMM with plasmacytoma of bone who presented with severe hypercalcemia, acute kidney injury and a large thoracal mass on chest X-ray masquerading as lung cancer.</description><subject>acute kidney injury</subject><subject>Acute Kidney Injury - etiology</subject><subject>Adult</subject><subject>Bone cancer</subject><subject>Bone marrow</subject><subject>Bone mass</subject><subject>Bone Neoplasms - complications</subject><subject>Bone Neoplasms - diagnosis</subject><subject>Bone Neoplasms - diagnostic imaging</subject><subject>Cell lineage</subject><subject>Cell proliferation</subject><subject>Chest</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Hypercalcemia</subject><subject>Injuries</subject><subject>Ionizing radiation</subject><subject>Kidney</subject><subject>Lung cancer</subject><subject>Lung Neoplasms - diagnosis</subject><subject>Lymphocytes B</subject><subject>Male</subject><subject>masquerader</subject><subject>Multiple myeloma</subject><subject>Multiple Myeloma - complications</subject><subject>Multiple Myeloma - diagnosis</subject><subject>Multiple Myeloma - diagnostic imaging</subject><subject>nonsecretory multiple myeloma</subject><subject>Plasma cells</subject><subject>Plasmacytoma</subject><subject>Plasmacytoma - complications</subject><subject>Plasmacytoma - diagnosis</subject><subject>Plasmacytoma - diagnostic imaging</subject><subject>plasmacytoma of bone</subject><subject>Radiography</subject><subject>Urine</subject><issn>0918-2918</issn><issn>1349-7235</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUtPGzEUhS3UCgLtX6i8YzXBj3m5uxBRQISCqnZteTx3wJHHk9oeVSPx43GUkAVi0SvrXsn3O8eyDkKYkjmjpbgwLoJ3yvbQGm0czHMx5xURR2hGeS6yivHiE5oRQeuMpXaCTkNYE8LrSrBjdMKI4CTP2Qy9LPAv5QHfq_B3BK9a8Hjo8Gp0T3ipnAb_Hf8cXADtIQ5-wvejjWZjk2ICO_QK_zPxGT9aFXqlp7i9SfrLwQF-9BDARZOsVMALPUbAd6Z1MOFbtx799AV97pQN8HU_z9CfH1e_lzfZ6uH6drlYZbogPGZ1wVVDgdKKNE2nGt7qmpQCGGek7ThUdS0IbXU6jLZNqqIqak5JVSQF4_wMne98N35IvwxR9iZosFY5GMYgBamSd16S_yLLkrMykfWO1H4IwUMnN970yk-SErkNSb4PSeZCbkNK0m_7R8YmLQ_Ct1QS8LAD1iGqJzgAykejLXzoTMW-M8r5gdTPyktw_BWw37EP</recordid><startdate>20100101</startdate><enddate>20100101</enddate><creator>Guney, Ibrahim</creator><creator>Solak, Yalcin</creator><creator>Atalay, Huseyin</creator><creator>Altintepe, Lutfullah</creator><creator>Tonbul, H. Zeki</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7QP</scope></search><sort><creationdate>20100101</creationdate><title>A Rare Masquerader of Lung Cancer: Nonsecretory Multiple Myeloma with Plasmacytoma of Bone Presenting as Acute Kidney Injury</title><author>Guney, Ibrahim ; Solak, Yalcin ; Atalay, Huseyin ; Altintepe, Lutfullah ; Tonbul, H. Zeki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-853ab1e1170bbfab3dc8069e2320df3e788901dc1dc21dbbbb57583107570b233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>acute kidney injury</topic><topic>Acute Kidney Injury - etiology</topic><topic>Adult</topic><topic>Bone cancer</topic><topic>Bone marrow</topic><topic>Bone mass</topic><topic>Bone Neoplasms - complications</topic><topic>Bone Neoplasms - diagnosis</topic><topic>Bone Neoplasms - diagnostic imaging</topic><topic>Cell lineage</topic><topic>Cell proliferation</topic><topic>Chest</topic><topic>Diagnosis, Differential</topic><topic>Humans</topic><topic>Hypercalcemia</topic><topic>Injuries</topic><topic>Ionizing radiation</topic><topic>Kidney</topic><topic>Lung cancer</topic><topic>Lung Neoplasms - diagnosis</topic><topic>Lymphocytes B</topic><topic>Male</topic><topic>masquerader</topic><topic>Multiple myeloma</topic><topic>Multiple Myeloma - complications</topic><topic>Multiple Myeloma - diagnosis</topic><topic>Multiple Myeloma - diagnostic imaging</topic><topic>nonsecretory multiple myeloma</topic><topic>Plasma cells</topic><topic>Plasmacytoma</topic><topic>Plasmacytoma - complications</topic><topic>Plasmacytoma - diagnosis</topic><topic>Plasmacytoma - diagnostic imaging</topic><topic>plasmacytoma of bone</topic><topic>Radiography</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guney, Ibrahim</creatorcontrib><creatorcontrib>Solak, Yalcin</creatorcontrib><creatorcontrib>Atalay, Huseyin</creatorcontrib><creatorcontrib>Altintepe, Lutfullah</creatorcontrib><creatorcontrib>Tonbul, H. 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Med.</addtitle><date>2010-01-01</date><risdate>2010</risdate><volume>49</volume><issue>19</issue><spage>2133</spage><epage>2135</epage><pages>2133-2135</pages><issn>0918-2918</issn><issn>1349-7235</issn><eissn>1349-7235</eissn><abstract>Multiple myeloma (MM) is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells which produce immunglobulins. If a monoclonal spike is not found in serum or urine but the patient has clinical findings and bone marrow plasma cell infiltration suggestive of MM, then the patient may have a rare subtype known as nonsecretory multiple myeloma (NSMM). 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| fulltext | fulltext |
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| ispartof | Internal Medicine, 2010, Vol.49(19), pp.2133-2135 |
| issn | 0918-2918 1349-7235 1349-7235 |
| language | eng |
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| source | MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | acute kidney injury Acute Kidney Injury - etiology Adult Bone cancer Bone marrow Bone mass Bone Neoplasms - complications Bone Neoplasms - diagnosis Bone Neoplasms - diagnostic imaging Cell lineage Cell proliferation Chest Diagnosis, Differential Humans Hypercalcemia Injuries Ionizing radiation Kidney Lung cancer Lung Neoplasms - diagnosis Lymphocytes B Male masquerader Multiple myeloma Multiple Myeloma - complications Multiple Myeloma - diagnosis Multiple Myeloma - diagnostic imaging nonsecretory multiple myeloma Plasma cells Plasmacytoma Plasmacytoma - complications Plasmacytoma - diagnosis Plasmacytoma - diagnostic imaging plasmacytoma of bone Radiography Urine |
| title | A Rare Masquerader of Lung Cancer: Nonsecretory Multiple Myeloma with Plasmacytoma of Bone Presenting as Acute Kidney Injury |
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