Binding of 2-acetylaminofluorene to DNA

2-Acetylaminofluorene (2-AAF) is a carcinogenic and mutagenic derivative of fluorene. It is used as a biochemical tool in the study of carcinogenesis. Studies have shown that it induces tumors in a number of species in the liver, bladder, and kidney. It is thought that 2-AAF-DNA adduct formation lea...

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Veröffentlicht in:	DNA and cell biology 2011-11, Vol.30 (11), p.955-962
Hauptverfasser:	Nafisi, Shohreh, Bonsaii, Mahyar, Alexis, Valerie, Glick, James
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acetylaminofluorene - metabolism 2-Acetylaminofluorene - pharmacology Animals Base Sequence Carcinogens - metabolism Carcinogens - pharmacology Cattle DNA - chemistry DNA - genetics DNA - metabolism Models, Molecular Nucleic Acid Conformation - drug effects Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared
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