Acute kidney injury in human leptospirosis: an immunohistochemical study with pathophysiological correlation

Tubulointerstitial nephritis is a common clinicopathological finding in leptospirosis. Clinically, nonoliguric acute kidney injury (AKI), hypokalemia, sodium, and magnesium wasting frequently occur in leptospirosis. The exact mechanisms of renal involvement remain largely unclear. Immunohistochemist...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2010-04, Vol.456 (4), p.367-375
Hauptverfasser:	Araujo, Eduardo Rocha, Seguro, Antonio Carlos, Spichler, Anne, Magaldi, Antonio J., Volpini, Rildo A., De Brito, Thales
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - metabolism Acute Kidney Injury - microbiology Acute Kidney Injury - physiopathology Adolescent Adult Aged Aged, 80 and over Aquaporin 1 - metabolism Aquaporin 2 - metabolism Autopsy Bacterial diseases Biological and medical sciences Female Human bacterial diseases Humans Infectious diseases Investigative techniques, diagnostic techniques (general aspects) Kidney - microbiology Kidney - pathology Kidney Tubules - metabolism Kidney Tubules - pathology Kidney Tubules - physiopathology Kidneys Leptospira Leptospira - isolation & purification Leptospirosis - complications Leptospirosis - metabolism Leptospirosis - physiopathology Magnesium Male Medical sciences Medicine Medicine & Public Health Middle Aged Miscellaneous Necrosis Nephrology. Urinary tract diseases Original Article Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Sodium Sodium-Hydrogen Exchanger 3 Sodium-Hydrogen Exchangers - metabolism Sodium-Potassium-Chloride Symporters - metabolism Sodium-Potassium-Exchanging ATPase - metabolism Solute Carrier Family 12, Member 1 Urinary system involvement in other diseases. Miscellaneous Water transport
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