Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs

The International Agency for Research on Cancer has classified several antineoplastic drugs in Group 1 (human carcinogens), among which chlorambucil, cyclophosphamide (CP) and tamoxifen, Group 2A (probable human carcinogens), among which cisplatin, etoposide, N-ethyl- and N-methyl-N-nitrosourea, and...

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Veröffentlicht in:	Mutagenesis 2011-05, Vol.26 (3), p.359-369
Hauptverfasser:	VILLARINI, Milena, DOMINICI, Luca, PICCININI, Renza, FATIGONI, Cristina, AMBROGI, Maura, CURTI, Gianluca, MORUCCI, Piero, MUZI, Giacomo, MONARCA, Silvano, MORETTI, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - analysis Antineoplastic Agents - toxicity Biological and medical sciences Cancer Care Facilities Comet Assay Cytarabine - analysis Cytarabine - urine DNA Damage - genetics Fluorouracil - analysis Fundamental and applied biological sciences. Psychology Genotype Glutathione S-Transferase pi - genetics Glutathione Transferase - genetics Humans Italy Molecular and cellular biology Molecular genetics Mutagenesis. Repair Nursing Staff, Hospital Occupational Exposure - analysis Occupational Exposure - statistics & numerical data Polymorphism, Restriction Fragment Length Regression Analysis Statistics, Nonparametric Tumor Suppressor Protein p53 - genetics
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