Regulation of Epidermal Tight-Junctions (TJ) during Infection with Exfoliative Toxin-Negative Staphylococcus Strains

Tight Junction (TJ) proteins have been shown to exert a barrier function within the skin. Here, we study the fate of TJ proteins during the challenge of the skin by bacterial colonization and infection. We investigated the influence of various exfoliative toxin-negative Staphylococcus strains on TJ,...

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Veröffentlicht in:	Journal of investigative dermatology 2008-04, Vol.128 (4), p.906-916
Hauptverfasser:	Ohnemus, Ulrich, Kohrmeyer, Klaas, Houdek, Pia, Rohde, Holger, Wladykowski, Ewa, Vidal, Sabine, Horstkotte, Matthias A., Aepfelbacher, Martin, Kirschner, Nina, Behne, Martin J., Moll, Ingrid, Brandner, Johanna M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Adherens Junctions - metabolism Animals Bacterial diseases Biological and medical sciences Dermatology Desmosomes - metabolism Disease Models, Animal Epidermis - metabolism Epidermis - microbiology Human bacterial diseases Humans Infectious diseases Medical sciences Membrane Proteins - analysis Membrane Proteins - metabolism Occludin Phosphoproteins - metabolism Staphylococcal Infections - metabolism Staphylococcal Infections - microbiology Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Staphylococcus epidermidis Tight Junctions - chemistry Tight Junctions - metabolism Tight Junctions - microbiology Zonula Occludens-1 Protein
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