Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF- Kappa B-dependent pathway

Introduction: Methotrexate (MTX) induces macrophage apoptosis in vitro, but there is not much evidence for increased synovial macrophage apoptosis in MTX-treated patients. Macrophage apoptosis is reported, however, during clinical response to anti-tumor necrosis factor-alpha (TNF- alpha ) treatments...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Arthritis research & therapy 2011-01, Vol.13 (1)
Hauptverfasser:	Lo, SZY, Steer, J H, Joyce, DA
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!