TH1/TH17 profiles in crohn's disease: a cross sectional single centre study in postoperative crohn's disease

Introduction Th1 and Th17 pathways are implicated in Crohn's disease (CD). In operative resection samples healthy ileum shows high TGFβ levels in patients who develop recurrence, with TGFβ being a known activator of the Th17 response. Other studies in CD show a dominant Th1 cytokine profile, wi...

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Veröffentlicht in:	Gut 2011-04, Vol.60 (Suppl 1), p.A212-A212
Hauptverfasser:	Murugananthan, A U, Bernardo, D, Tozer, P, Tee, C T, Mann, E, Hart, A L, Arebi, N, Knight, S C, Al-Hassi, H O
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Cell culture Colon Crohn's disease Cytokines Endoscopy Flow cytometry Helper cells Ileum Inflammation Inflammatory bowel diseases Infliximab Interleukin 10 Interleukin 12 Interleukin 17 Interleukin 2 Interleukin 23 Interleukin 4 Interleukin 6 Lymphocytes T Monoclonal antibodies Parathyroid hormone postoperative Crohn's disease Statistical analysis TH1/TH17 Tumor necrosis factor-α γ-Interferon
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