Can clinical and molecular epidemiologic parameters guide empiric treatment with vancomycin for methicillin-resistant Staphylococcus aureus infections?

Abstract Reports of vancomycin treatment failure for infections caused by susceptible methicillin-resistant Staphylococcus aureus (MRSA) strains with elevated minimum inhibitory concentration (MIC) has prompted use of high-dose therapy, but nephrotoxicity is a concern. We determined whether clinical...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2011-05, Vol.70 (1), p.124-130
Hauptverfasser:	Yamaki, Jason, Lee, Michelle, Shriner, Kimberly A, Wong-Beringer, Annie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Bacterial Typing Techniques Bacteriology Biological and medical sciences DNA, Bacterial - genetics Female Fundamental and applied biological sciences. Psychology Genotype Humans Infectious Disease Infectious diseases Internal Medicine Male Medical sciences Methicillin-Resistant Staphylococcus aureus - classification Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - genetics Methicillin-Resistant Staphylococcus aureus - isolation & purification Microbial Sensitivity Tests Microbiology Middle Aged Miscellaneous Molecular Epidemiology Molecular Typing MRSA PVL Resistance Staphylococcal Infections - drug therapy Staphylococcal Infections - epidemiology Staphylococcal Infections - microbiology Staphylococcus aureus Susceptibility Vancomycin Vancomycin - pharmacology Vancomycin - therapeutic use
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